GPR108 and TMEM243

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR108	TMEM243
Description		G protein-coupled receptor 108	transmembrane protein 243
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Membrane Cis-Golgi Network Membrane	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Immune Response Defense Response To Virus Type I Interferon-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Lung cancer in never smokers ( 28604730) Schizophrenia ( 29483656)
Interacting Genes		11 interacting genes: CD53 FAM209A GJA8 GLP1R KIR2DL3 LMNA LRSAM1 MTERF3 MUC1 NEMP1 TMEM243	46 interacting genes: AQP6 BIK CD33 CD74 CD79A CISD2 CLEC14A CPLX4 CREB3 EBP ELOVL4 ELOVL5 ERGIC3 FAM174A FAM209A FFAR2 GJA8 GPR108 GPR152 GPR37L1 GPX8 HSD17B13 JAGN1 KIR2DL3 LIME1 LMNA LRP10 MRM1 MTIF3 MUC1 PLP1 PSCA RETREG3 RMDN3 SAR1A SCN3B SEC11C SLC10A6 SSMEM1 TMEM101 TMEM14B TMEM35A TMEM45B TMEM80 TMPRSS2 ZFYVE27
Entrez ID		56927	79161
HPRD ID		18896	12911
Ensembl ID		ENSG00000125734	ENSG00000135185
Uniprot IDs		G5E9L6 Q9NPR9	C9JY04 Q9BU79
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum B Cell Receptor Complex Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Acetylcholine Receptor Regulator Activity Protein Binding Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Negative Regulation Of Peptide Secretion Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Endoplasmic Reticulum Organization Fatty Acid Elongation
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