PRPSAP2 and ENDOV

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PRPSAP2	ENDOV
Description		phosphoribosyl pyrophosphate synthetase associated protein 2	endonuclease V
Image
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleolus Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	Magnesium Ion Binding Enzyme Inhibitor Activity Protein Binding Enzyme Regulator Activity Identical Protein Binding	Magnesium Ion Binding DNA Binding RNA Binding Single-stranded RNA Binding Nuclease Activity Endonuclease Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds DNA Endonuclease Activity, Producing 5'-phosphomonoesters RNA Endonuclease Activity Producing 5'-phosphomonoesters, Hydrolytic Mechanism Metal Ion Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleotide Biosynthetic Process Bone Development	DNA Repair
Pathways
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Pancreatic cancer ( 20686608)	Total intracranial volume ( 31530798)
Interacting Genes		3 interacting genes: APP ENDOV TEX11	2 interacting genes: NELFCD PRPSAP2
Entrez ID		5636	284131
HPRD ID		04789	08758
Ensembl ID		ENSG00000141127	ENSG00000173818
Uniprot IDs		O60256	Q8N8Q3
PDB IDs		2JI4	4NSP 6OZE
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Gene Conversion Male Meiosis Chromosome Segregation Meiotic Gene Conversion DNA Endonuclease Activity, Producing 5'-phosphomonoesters Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling RNA Endonuclease Activity Producing 5'-phosphomonoesters, Hydrolytic Mechanism Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Chiasma Assembly Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Central Element Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding	5-phosphoribose 1-diphosphate Biosynthetic Process NELF Complex Enzyme Regulator Activity Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation By RNA Polymerase II
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