PRPSAP2 and ENDOV

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PRPSAP2	ENDOV
Gene Name		phosphoribosyl pyrophosphate synthetase-associated protein 2	endonuclease V
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex	Nucleolus Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity	Magnesium Ion Binding Single-stranded RNA Binding Endodeoxyribonuclease Activity, Producing 5'-phosphomonoesters Endoribonuclease Activity, Producing 5'-phosphomonoesters Structure-specific DNA Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity Bone Development	DNA Catabolic Process, Endonucleolytic DNA Repair RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 20686608)
Protein-Protein Interactions		2 interactors: APP ENDOV	2 interactors: NELFCD PRPSAP2
Entrez ID		5636	284131
HPRD ID		04789	08758
Ensembl ID		ENSG00000141127	ENSG00000173818
Uniprot IDs		B4E329 O60256	Q8N8Q3
PDB IDs		2JI4
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth DNA Catabolic Process, Endonucleolytic Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis Cholesterol Metabolic Process Adult Locomotory Behavior
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