WSB2 and RPN1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		WSB2	RPN1
Description		WD repeat and SOCS box containing 2	ribophorin I
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Oligosaccharyltransferase Complex Membrane Melanosome Oligosaccharyltransferase Complex A Oligosaccharyltransferase Complex B
	Molecular Function	Protein Binding	RNA Binding Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Intracellular Signal Transduction	Protein Glycosylation Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine
Pathways		Neddylation	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs
Diseases
GWAS		Chronic rhinosinusitis ( 33393196) Red blood cell count ( 32888494)	Blood protein levels ( 30072576) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil count ( 27863252 29403010) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mild to moderate chronic kidney disease ( 31178898) Monocyte count ( 23314186 32888494 29403010 27863252) Monocyte percentage of white cells ( 27863252 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil count ( 32888494) Platelet distribution width ( 32888494) Serum metabolite levels ( 33031748) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 21738480 32888494) White blood cell count (basophil) ( 29403010)
Interacting Genes		3 interacting genes: CSF3R EZH2 RPN1	18 interacting genes: ADRM1 DPF1 DUX4 ERBB3 HSPA5 KRTAP1-3 PSMC2 RAD23A RBBP4 RBFOX2 SGTA SIGIRR SMARCB1 UBC UBQLN1 UBQLN2 UBQLN4 WSB2
Entrez ID		55884	6184
HPRD ID		18305	01598
Ensembl ID		ENSG00000176871	ENSG00000163902
Uniprot IDs		Q9NYS7	P04843
PDB IDs			6S7O 6S7T 8B6L 8PN9
Enriched GO Terms of Interacting Partners?		Granulocyte Colony-stimulating Factor Binding Hepatocyte Homeostasis Cellular Response To Trichostatin A Histone H3K27 Trimethyltransferase Activity Response To Tetrachloromethane Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Amelogenesis Regulation Of Retinoic Acid Receptor Signaling Pathway Cellular Response To Antibiotic Cardiac Muscle Hypertrophy In Response To Stress ESC/E(Z) Complex Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Pronucleus Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Phosphorylation Primary MiRNA Binding Histone H3K27 Methyltransferase Activity G1 To G0 Transition Subtelomeric Heterochromatin Formation Facultative Heterochromatin Formation Negative Regulation Of Epidermal Cell Differentiation Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Dendrite Development Cerebellar Cortex Development Chromatin Silencing Complex Oligosaccharyltransferase Complex B Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Oligosaccharyltransferase Complex Oligosaccharyltransferase Complex A Negative Regulation Of Nitric Oxide Biosynthetic Process Nitric-oxide Synthase Regulator Activity Intraciliary Retrograde Transport DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of DNA-templated DNA Replication	Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Proteasome Complex Regulation Of Cellular Response To Stress Positive Regulation Of ERAD Pathway Proteolysis Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of G0 To G1 Transition Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Macromolecule Metabolic Process Protein Metabolic Process Autophagosome Regulation Of Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Protein-containing Complex NBAF Complex Autophagosome Assembly Proteasome Binding Cytosol Autophagosome Organization Nucleoplasm Autophagy Regulation Of Primary Metabolic Process Regulation Of Nucleotide-excision Repair Regulation Of Double-strand Break Repair Nucleosomal DNA Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Vacuole Organization Negative Regulation Of Transport
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