MREG and HNRNPLL

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		MREG	HNRNPLL
Description		melanoregulin	heterogeneous nuclear ribonucleoprotein L like
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Late Endosome Membrane Protein-containing Complex Melanosome Membrane Melanosome	Nucleus Membrane Synapse Ribonucleoprotein Complex
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Melanocyte Differentiation Melanosome Localization Melanosome Transport Pigmentation Developmental Pigmentation Minus-end-directed Organelle Transport Along Microtubule Phagosome Maturation	MRNA Processing Positive Regulation Of RNA Splicing Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Coronary artery disease ( 32469254) Macular thickness ( 30535121) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)	Body mass index ( 28892062)
Interacting Genes		6 interacting genes: CFTR CPSF7 EIF1AD HNRNPLL MAP1LC3A PUF60	57 interacting genes: ADAMTSL4 ATXN1 BANP BARD1 BCAS2 BHLHE40 BOLL CALCOCO2 CEBPA DAB1 DDX39A DDX39B DENND2D EFHC2 EIF4ENIF1 FAM9B GOPC HNRNPK HOOK1 IKZF3 KHDRBS2 KRT31 KRT40 KRTAP10-3 MAGED1 MDFI MID2 MREG PAXIP1 PCBP1 PCBP3 PNMA1 POLR1F PRPF6 PTBP1 QKI RBM10 RBM3 RBPMS REL RHOXF2 SKIL SNRPA SPRY2 SRSF11 SSX2IP SUMO2 TADA2A THAP1 TLE5 TMCC2 TRIM23 TRIM27 UBE2I USP10 VAC14 WEE2-AS1
Entrez ID		55686	92906
HPRD ID		07645	13667
Ensembl ID		ENSG00000118242	ENSG00000143889
Uniprot IDs		Q8N565	A0A0S2Z6K1 A8K894 Q8WVV9
PDB IDs			7EVS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding MRNA Processing RNA Binding Nucleic Acid Binding MRNA Metabolic Process Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization MRNA Alternative Polyadenylation Cellular Response To Oxygen-glucose Deprivation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Regulation Of RNA Splicing RNA Processing MRNA Cleavage Factor Complex Response To Iron(II) Ion Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway MRNA Binding Cellular Response To Nitrogen Starvation Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway Response To Oxygen-glucose Deprivation Autolysosome Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Phosphatidylethanolamine Binding Cellular Response To Forskolin Protein Heterotetramerization Response To Forskolin MRNA Cleavage And Polyadenylation Specificity Factor Complex Chloride Transmembrane Transporter Activity Sperm Capacitation Response To Lead Ion Ribonucleoprotein Complex	Nucleic Acid Binding Identical Protein Binding RNA Binding Regulation Of MRNA Processing MRNA Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Processing RNA Splicing Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process PML Body MRNA Metabolic Process Nucleus Regulation Of RNA Splicing Regulation Of Transcription By RNA Polymerase II Nuclear Speck RNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Splicing Nucleic Acid Metabolic Process Regulation Of Gene Expression Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Response To Cytokine Response To Peptide Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process SUMO Transferase Activity Regulation Of Metabolic Process Spliceosomal Complex Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process MRNA Stabilization Nuclear Export Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process
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