SYBU and DTNBP1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		SYBU	DTNBP1
Gene Name		syntabulin (syntaxin-interacting)	dystrobrevin binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Mitochondrion Microtubule Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Vesicle Intracellular Membrane-bounded Organelle Dense Body	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Postsynaptic Density Sarcoplasm Cell Junction Axon Growth Cone Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane
	Molecular Function	Protein Binding Microtubule Binding Syntaxin-1 Binding Kinesin Binding	Protein Binding
	Biological Process	Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Positive Regulation Of Neurotransmitter Secretion Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Melanosome Organization Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Membrane Organization
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ATXN1 DISC1 DTNBP1 EXOC1 KIF5B RPL29	53 interactors: ABI3 AKAP6 ARFIP2 BLOC1S5 BLOC1S6 BRF1 BRK1 C19orf66 CCDC146 CCDC153 CCDC53 CCHCR1 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 EXOC4 EXOC7 GLTSCR1L HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 MACF1 NBEA NDN NUF2 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SNAPIN SRGAP3 SSC5D SYBU SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM32 TRIM9 TXLNB ZNF490
Entrez ID		55638	84062
HPRD ID		07902	06190
Ensembl ID		ENSG00000147642	ENSG00000047579
Uniprot IDs		B7Z4D2 Q9NX95	D6RJC6 Q96EV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Localization Establishment Of Localization In Cell Intracellular Transport Positive Regulation Of Synaptic Transmission Microtubule-based Transport Stress Granule Disassembly Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Membrane Organization Establishment Of Vesicle Localization Vesicle Localization Plus-end-directed Vesicle Transport Along Microtubule Multicellular Organismal Development Regulation Of Dopamine Receptor Signaling Pathway Cytoplasm Organization Regulation Of Membrane Potential Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Platelet Dense Granule Organization Regulation Of Synaptic Transmission Microtubule-based Movement Establishment Of Organelle Localization Developmental Process Regulation Of Signaling Positive Regulation Of Neurotransmitter Secretion Organelle Organization Positive Regulation Of Synaptic Transmission, GABAergic Movement Of Cell Or Subcellular Component Mitochondrial Calcium Ion Homeostasis Organelle Localization Generation Of Neurons Regulation Of Synapse Maturation Anterograde Synaptic Vesicle Transport Melanosome Organization Regulation Of Dopamine Secretion TOR Signaling Pigment Granule Organization Neurogenesis Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Neuroblast Proliferation Anterograde Axon Cargo Transport Positive Regulation Of Potassium Ion Transport Synaptic Transmission Protein Localization Vesicle Transport Along Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Ion Transport Organelle Disassembly	Establishment Of Localization In Cell Movement Of Cell Or Subcellular Component Cellular Pigmentation Cellular Localization Endosomal Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Organelle Organization Intracellular Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Organelle Localization Microtubule-based Process Vesicle-mediated Transport Microtubule-based Movement Establishment Of Vesicle Localization Establishment Of Organelle Localization Pigmentation Vesicle Localization Protein Localization Protein Transport Anterograde Synaptic Vesicle Transport Establishment Of Protein Localization Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Exocytosis Secretion By Cell Cell Projection Organization Synaptic Vesicle Transport Positive Regulation Of Cell Growth Endosome To Melanosome Transport Pigment Granule Maturation Axon Cargo Transport Small GTPase Mediated Signal Transduction Secretion Synaptic Vesicle Exocytosis Cellular Pigment Accumulation Nervous System Development Regulation Of Calcineurin-NFAT Signaling Cascade Cytoplasmic Transport Transport Positive Regulation Of Pigment Cell Differentiation Mitotic Nuclear Division Neuron Development Positive Regulation Of Developmental Pigmentation Negative Regulation Of Viral Release From Host Cell Generation Of Neurons
Tagcloud ?			additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Difference) ?			additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Intersection) ?