PRR5 and TTC38

		PRR5	TTC38
Description		proline rich 5	tetratricopeptide repeat domain 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Positive Regulation Of Cell Growth Cellular Response To Nutrient Levels TORC2 Signaling Negative Regulation Of Apoptotic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)	Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1	2 interacting genes: PFDN1 TK1
Entrez ID		55615	55020
HPRD ID		18696	07943
Ensembl ID		ENSG00000186654	ENSG00000075234
Uniprot IDs		P85299	Q5R3I4
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemoattraction Of Dopaminergic Neuron Axon Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Lobar Bronchus Development Trachea Cartilage Morphogenesis Renal Outer Medulla Development Outer Medullary Collecting Duct Development Bronchus Development Chemoattraction Of Axon Metanephric Loop Of Henle Development Inner Medullary Collecting Duct Development Renal Inner Medulla Development ESCRT-0 Complex	Prefoldin Complex DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Deoxyribonucleoside Monophosphate Biosynthetic Process TORC2 Complex Pyrimidine Nucleoside Metabolic Process Negative Regulation Of Amyloid Fibril Formation TORC2 Signaling Regulation Of Amyloid Fibril Formation Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleoside Metabolic Process
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