GALNT10 and MUC7

Number of citations of the paper that reports this interaction (PubMedID 12417297)
0

Data Source:
HPRD (in vitro)

		GALNT10	MUC7
Description		polypeptide N-acetylgalactosaminyltransferase 10	mucin 7, secreted
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Extracellular Region Golgi Lumen Plasma Membrane Extracellular Exosome
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine	Killing Of Cells Of Another Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		O-linked glycosylation of mucins	Defective GALNT3 causes HFTC Defective C1GALT1C1 causes TNPS Defective GALNT12 causes CRCS1 Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 23583978 25673413 21701570) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 30285260 29483656 25056061) Triglyceride levels ( 32203549)	Diabetic nephropathy in type 1 diabetes ( 31537649)
Interacting Genes		3 interacting genes: CNOT2 MUC1 MUC7	8 interacting genes: AMY1A GALNT10 GALNT12 GALNT14 HTN3 LTF PCGF1 SELL
Entrez ID		55568	4589
HPRD ID		12157	11759
Ensembl ID		ENSG00000164574	ENSG00000171195
Uniprot IDs		Q86SR1	Q8TAX7
PDB IDs		2D7I 2D7R
Enriched GO Terms of Interacting Partners?		Transcription Coregulator Activity TCR Signalosome Golgi Lumen Regulation Of Stem Cell Population Maintenance SMN-Gemin2 Complex Non-sequence-specific DNA Binding, Bending	Polypeptide N-acetylgalactosaminyltransferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Carbohydrate Binding Metal Ion Binding Protein O-linked Glycosylation Protein Glycosylation Macromolecule Glycosylation Glycosylation Glycosyltransferase Activity Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Defense Response To Fungus Response To Fungus Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Alpha-amylase Activity Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Carbohydrate Derivative Biosynthetic Process Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Killing Of Cells Of Another Organism Positive Regulation Of Bone Mineralization Involved In Bone Maturation Phagocytic Vesicle Lumen Membrane Destabilizing Activity Antimicrobial Humoral Response Heparin Binding Negative Regulation Of Osteoclast Development Golgi Membrane Extracellular Space Glycosphingolipid Binding Cell Killing Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development Carbohydrate Derivative Metabolic Process Cytolysis By Host Of Symbiont Cells Antifungal Humoral Response Chloride Ion Binding Humoral Immune Response Negative Regulation Of ATP-dependent Activity Negative Regulation Of Membrane Potential Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Osteoblast Proliferation Oligosaccharide Binding Specific Granule Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cation Binding Host-mediated Suppression Of Viral Proces Defense Response To Bacterium
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?