PRCC and PPIL2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		PRCC	PPIL2
Gene Name		papillary renal cell carcinoma (translocation-associated)	peptidylprolyl isomerase (cyclophilin)-like 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Golgi Lumen Plasma Membrane
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Ligase Activity Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cell Cycle Checkpoint	Protein Polyubiquitination Protein Peptidyl-prolyl Isomerization Protein Folding Blood Coagulation Leukocyte Migration Protein Localization To Plasma Membrane
Pathways			Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CSNK2A1 EGFR LSM2 MAD2L2 PPIL2 PRPF19 RBM10 SRSF2 TOE1	7 interactors: APP BSG CALM1 CRNKL1 HSP90AA1 PRCC TRIM23
Entrez ID		5546	23759
HPRD ID		01562	08472
Ensembl ID		ENSG00000143294	ENSG00000100023
Uniprot IDs		A6NG79 Q92733 Q96FT4	E7EW80 Q13356
PDB IDs			1ZKC
Enriched GO Terms of Interacting Partners?		RNA Splicing Negative Regulation Of Protein Catabolic Process MRNA Processing Negative Regulation Of Cell Cycle Gene Expression MRNA Metabolic Process RNA Processing Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition RNA Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cell Cycle Process Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Alkanesulfonate Metabolic Process Generation Of Catalytic Spliceosome For First Transesterification Step Negative Regulation Of Chromosome Organization Signal Transduction In Response To DNA Damage Regulation Of Cell Cycle Process Cell Cycle Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Double-strand Break Repair Cellular Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Checkpoint Heterocycle Metabolic Process Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Activation Of Phospholipase A2 Activity Negative Regulation Of APC-Cdc20 Complex Activity Cellular Aromatic Compound Metabolic Process Protein Polyubiquitination	Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Nitric-oxide Synthase Activity Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Oxidoreductase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Reactive Oxygen Species Metabolic Process Wound Healing Synaptic Growth At Neuromuscular Junction Response To Wounding Collateral Sprouting In Absence Of Injury Protein Import Into Mitochondrial Outer Membrane Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Innate Immune Response Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity Establishment Of Localization In Cell Membrane Organization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cell Cycle Immune System Process Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Small Molecule Metabolic Process Fc Receptor Signaling Pathway Neuron Remodeling Regulation Of Catalytic Activity Cellular Localization Response To Abiotic Stimulus Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Response To Metal Ion Positive Regulation Of Phosphoprotein Phosphatase Activity Chaperone-mediated Protein Complex Assembly Response To Light Stimulus Exocytosis Alcohol Metabolic Process Locomotion Protein Localization To Membrane Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Immune Response
Tagcloud ?		1g 4179delct ages bilateral develops e1351 exome germline heterozygosity hit kidneys multifocal nephrectomies nephrectomy ngs nonsilent papillary r1032 r1713h r905q rccs second seizures shower tsc tsc2 tuberous typically	acidic assayed bace1 changing cleaving cyclophilin drive employing enolase fibrillary fruitful gfap glial isomerase limiting modulator mortem neuron nse peptidylprolyl proteolytic qbase qpcr quantified reticulon rtn3 secretase stably track
Tagcloud (Difference) ?		1g 4179delct ages bilateral develops e1351 exome germline heterozygosity hit kidneys multifocal nephrectomies nephrectomy ngs nonsilent papillary r1032 r1713h r905q rccs second seizures shower tsc tsc2 tuberous typically	acidic assayed bace1 changing cleaving cyclophilin drive employing enolase fibrillary fruitful gfap glial isomerase limiting modulator mortem neuron nse peptidylprolyl proteolytic qbase qpcr quantified reticulon rtn3 secretase stably track
Tagcloud (Intersection) ?