PRCC and PPIL2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		PRCC	PPIL2
Description		proline rich mitotic checkpoint control factor	peptidylprolyl isomerase like 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Golgi Lumen Plasma Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Ubiquitin-protein Transferase Activity Protein Binding Transferase Activity Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Cell Cycle	Protein Polyubiquitination MRNA Processing Protein Folding RNA Splicing Protein Ubiquitination Protein Localization To Plasma Membrane
Pathways		mRNA Splicing - Major Pathway	Basigin interactions mRNA Splicing - Major Pathway
Drugs
Diseases		Renal cell carcinoma
GWAS		Sjögren's syndrome ( 28076899)	Bipolar disorder ( 31043756) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926)
Interacting Genes		8 interacting genes: CSNK2A1 EGFR HOMER3 MAD2L2 PPIL2 RBM10 SRSF2 TOE1	11 interacting genes: APP BSG CALM1 CEBPA CRNKL1 HSP90AA1 PLK1 PRCC SNAI1 TRIM23 ZNF830
Entrez ID		5546	23759
HPRD ID		01562	08472
Ensembl ID		ENSG00000143294	ENSG00000100023
Uniprot IDs		A0A0S2Z456 Q92733 Q96FT4	A0A7P0TBL3 A8K0I0 Q13356
PDB IDs			1ZKC 7ABI 7DVQ 7QTT 8CH6 8I0P 8I0R 8I0S 8I0T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Catabolic Process Negative Regulation Of Protein Catabolic Process MRNA Metabolic Process Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Nucleic Acid Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of DNA Repair RNA Metabolic Process Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA Recombination Negative Regulation Of Macromolecule Metabolic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Metabolic Process Multivesicular Body, Internal Vesicle Lumen RNA Processing RNA Splicing Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Protein Catabolic Process Regulation Of Chromosome Separation Regulation Of Cell Growth Regulation Of Double-strand Break Repair Via Homologous Recombination Nuclear Speck MRNA Processing Regulation Of Cell Cycle Phase Transition Shc-EGFR Complex PML Body Regulation Of DNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Regulation Of MRNA Splicing, Via Spliceosome Smooth Muscle Cell Apoptotic Process G Protein-coupled Glutamate Receptor Binding Regulation Of DNA Recombination Negative Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Chromosome Segregation Negative Regulation Of Biosynthetic Process Positive Regulation Of DNA Repair Epidermal Growth Factor Binding Regulation Of MRNA Processing Nucleic Acid Binding Negative Regulation Of Ribosome Biogenesis	Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Localization Positive Regulation Of Catabolic Process Regulation Of Cell Cycle Response To Metal Ion Notch Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Protein Localization To Nucleus Myelin Sheath Positive Regulation Of Proteolysis Amyloid-beta Complex Regulation Of Cell Junction Assembly Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Blood Circulation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Neuron Recognition Regulation Of Protein Localization Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Protein Transport Spindle Microtubule Cell Cycle G2/M Phase Transition G2/M Transition Of Mitotic Cell Cycle RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding CTP Binding DATP Binding Mitotic G2/M Transition Checkpoint Acetylcholine Receptor Activator Activity PTB Domain Binding Developmental Growth Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Metabolic Process Reproductive Process Positive Regulation Of Interleukin-6 Production Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Apoptotic Process Protein-containing Complex Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Protein Import
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