NPY4R and PPY

Number of citations of the paper that reports this interaction (PMID 7493937)
19

Data Source:
HPRD (in vitro)

		NPY4R	PPY
Gene Name		neuropeptide Y receptor Y4	pancreatic polypeptide
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity G-protein Coupled Receptor Activity Peptide Binding	G-protein Coupled Receptor Binding Receptor Binding Hormone Activity Neuropeptide Hormone Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Digestion Feeding Behavior Blood Circulation	Neuropeptide Signaling Pathway Cell-cell Signaling Digestion Feeding Behavior Protein Secretion Regulation Of Appetite
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: NPY PPY PYY	1 interactors: NPY4R
Entrez ID		5540	5539
HPRD ID		03476	01340
Ensembl ID		ENSG00000204174	ENSG00000108849
Uniprot IDs		P50391	P01298
PDB IDs		2IK5	1TZ4 1TZ5
Enriched GO Terms of Interacting Partners?		Regulation Of Appetite Neuropeptide Signaling Pathway Feeding Behavior Digestion Response To Nutrient Levels Response To Extracellular Stimulus Behavior Cell-cell Signaling G-protein Coupled Receptor Signaling Pathway Response To External Stimulus Positive Regulation Of Appetite Adult Feeding Behavior Cell Surface Receptor Signaling Pathway Regulation Of Response To Food Cell Proliferation Eating Behavior Signal Transduction Movement Of Cell Or Subcellular Component Signaling Central Nervous System Neuron Development Cell Communication Protein Secretion G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger	Neuropeptide Signaling Pathway Feeding Behavior Digestion
Tagcloud ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	ceph d17s181 d17s183 d17s190 d17s250 d17s507 d17s508 d17s509 d17s518 d17s579 d17s78 d17s791 d17s797 d17s80 d17s800 d17s806 d17s810 d17s855 d17s856 d17s857 d17s858 d17s859 edh17b epb3 gp3a hox2b kindreds krt10 thra1
Tagcloud (Difference) ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	ceph d17s181 d17s183 d17s190 d17s250 d17s507 d17s508 d17s509 d17s518 d17s579 d17s78 d17s791 d17s797 d17s80 d17s800 d17s806 d17s810 d17s855 d17s856 d17s857 d17s858 d17s859 edh17b epb3 gp3a hox2b kindreds krt10 thra1
Tagcloud (Intersection) ?