CPPED1 and COQ7

		CPPED1	COQ7
Description		calcineurin like phosphoesterase domain containing 1	coenzyme Q7, hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen	Nucleus Chromosome Mitochondrion Mitochondrial Inner Membrane Membrane Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Hydrolase Activity Metal Ion Binding	Chromatin Binding Monooxygenase Activity Protein Binding 3-demethoxyubiquinol 3-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Metal Ion Binding 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Ubiquinone Biosynthetic Process Determination Of Adult Lifespan Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Neutrophil degranulation	Ubiquinol biosynthesis
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Depression ( 29700475) Height ( 31562340) Type 2 diabetes ( 25760438)	Parkinson's disease ( 28892059)
Interacting Genes		1 interacting genes: POT1	1 interacting genes: COQ4
Entrez ID		55313	10229
HPRD ID		07735	03401
Ensembl ID		ENSG00000103381	ENSG00000167186
Uniprot IDs		Q9BRF8	Q99807
PDB IDs			7SSP 7SSS
Enriched GO Terms of Interacting Partners?		Delta1-piperideine-2-carboxylate Reductase Activity Thiomorpholine-carboxylate Dehydrogenase Activity 3-demethoxyubiquinol 3-hydroxylase Activity 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Ionotropic Glutamate Receptor Complex Lysine Catabolic Process Thyroid Hormone Binding Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Single-stranded Telomeric DNA Binding Telomerase Inhibitor Activity Shelterin Complex Establishment Of Protein Localization To Telomere Negative Regulation Of IRE1-mediated Unfolded Protein Response DEAD/H-box RNA Helicase Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding IRE1-mediated Unfolded Protein Response Thyroid Hormone Transport Telomeric Loop Disassembly Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Telomere Capping Caspase Binding Dendritic Spine Membrane Hormone Binding Ubiquinone Biosynthetic Process Regulation Of DNA Strand Elongation Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Modification Of Postsynaptic Structure Regulation Of Short-term Neuronal Synaptic Plasticity Ubiquinone Metabolic Process Thyroid Hormone Metabolic Process Quinone Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Striated Muscle Tissue Development Regulation Of Modification Of Synaptic Structure Positive Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening	4-hydroxy-3-methoxy-5-polyprenylbenzoate Decarboxylase Activity Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Ubiquinone Metabolic Process Ubiquinone Biosynthetic Process Quinone Metabolic Process Ketone Biosynthetic Process Ketone Metabolic Process Protein Serine/threonine Phosphatase Activity Azurophil Granule Lumen Lyase Activity
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