COQ7

Description		coenzyme Q7, hydroxylase
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GO Annotations	Cellular Component	Nucleus Chromosome Mitochondrion Mitochondrial Inner Membrane Membrane Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex
	Molecular Function	Chromatin Binding Monooxygenase Activity Protein Binding 3-demethoxyubiquinol 3-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Metal Ion Binding 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Ubiquinone Biosynthetic Process Determination Of Adult Lifespan Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Ubiquinol biosynthesis
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059)
Novel Interacting Genes		1 novel interacting genes: CPPED1
Interacting Genes		1 interacting genes: COQ4
Entrez ID		10229
HPRD ID		03401
Ensembl ID		ENSG00000167186
Uniprot IDs		Q99807
PDB IDs		7SSP 7SSS
Enriched GO Terms of Interacting Partners?		4-hydroxy-3-methoxy-5-polyprenylbenzoate Decarboxylase Activity Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Ubiquinone Metabolic Process Ubiquinone Biosynthetic Process Quinone Metabolic Process Ketone Biosynthetic Process Ketone Metabolic Process Protein Serine/threonine Phosphatase Activity Azurophil Granule Lumen Lyase Activity
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