PHF10 and CELSR2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PHF10	CELSR2
Gene Name		PHD finger protein 10	cadherin, EGF LAG seven-pass G-type receptor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	NpBAF Complex	Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Zinc Ion Binding	G-protein Coupled Receptor Activity Calcium Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development	Neuron Migration Cilium Movement Regulation Of Transcription, DNA-templated Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Wnt Signaling Pathway Ventricular System Development Neural Plate Anterior/posterior Regionalization Regulation Of Cell-cell Adhesion Regulation Of Protein Localization Cerebrospinal Fluid Secretion Cilium Assembly Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS		Type 1 diabetes ( 21980299)	Cardiovascular disease risk factors ( 21943158) Cholesterol, total ( 19060911 20686565) Coronary heart disease ( 21378988 21347282) LDL cholesterol ( 18262040 18179892 18193043 18193044 20864672 19060906 19060910 19060911 20686565) Lipid metabolism phenotypes ( 19936222) Lipoprotein-associated phospholipase A2 activity and mass ( 22003152) Metabolite levels ( 21909109) Myocardial infarction (early onset) ( 19198609) Progranulin levels ( 21087763) Response to statin therapy ( 20339536)
Protein-Protein Interactions		9 interactors: APLP1 CELSR2 L3MBTL2 LIG4 SETDB1 STAM2 UNC119 UTP14A VAV2	3 interactors: GARS KLF6 PHF10
Entrez ID		55274	1952
HPRD ID		11428	05040
Ensembl ID		ENSG00000130024	ENSG00000143126
Uniprot IDs		Q8WUB8	Q9HCU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis DNA Ligation Involved In DNA Recombination	Glycyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process
Tagcloud ?			adds arealization axon axons barrel conditional contexts forebrain fzd3 guidance guidepost inactivation mimics navigation pcp perturbs planar polarity projections redundantly thalamic thalamocortical thalamus unexpectedly vangl vangl1 vangl2 wiring
Tagcloud (Difference) ?			adds arealization axon axons barrel conditional contexts forebrain fzd3 guidance guidepost inactivation mimics navigation pcp perturbs planar polarity projections redundantly thalamic thalamocortical thalamus unexpectedly vangl vangl1 vangl2 wiring
Tagcloud (Intersection) ?