CELSR2

Gene Name		cadherin, EGF LAG seven-pass G-type receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	G-protein Coupled Receptor Activity Calcium Ion Binding
	Biological Process	Neuron Migration Cilium Movement Regulation Of Transcription, DNA-templated Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Wnt Signaling Pathway Ventricular System Development Neural Plate Anterior/posterior Regionalization Regulation Of Cell-cell Adhesion Regulation Of Protein Localization Cerebrospinal Fluid Secretion Cilium Assembly Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21943158) Cholesterol, total ( 19060911 20686565) Coronary heart disease ( 21378988 21347282) LDL cholesterol ( 18262040 18179892 18193043 18193044 20864672 19060906 19060910 19060911 20686565) Lipid metabolism phenotypes ( 19936222) Lipoprotein-associated phospholipase A2 activity and mass ( 22003152) Metabolite levels ( 21909109) Myocardial infarction (early onset) ( 19198609) Progranulin levels ( 21087763) Response to statin therapy ( 20339536)
Protein-protein Interactions		3 interactors: GARS KLF6 PHF10
Entrez ID		1952
HPRD ID		05040
Ensembl ID		ENSG00000143126
Uniprot IDs		Q9HCU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		adds arealization axon axons barrel conditional contexts forebrain fzd3 guidance guidepost inactivation mimics navigation pcp perturbs planar polarity projections redundantly thalamic thalamocortical thalamus unexpectedly vangl vangl1 vangl2 wiring