NOL8 and SNRNP40

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		NOL8	SNRNP40
Description		nucleolar protein 8	small nuclear ribonucleoprotein U5 subunit 40
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Sno(s)RNA-containing Ribonucleoprotein Complex Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	RRNA Processing Protein Localization To Nucleolus	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Malaria ( 31844061)	Alcohol dependence ( 23455491) Body mass index ( 26426971 29615537)
Interacting Genes		7 interacting genes: NIP7 RBFOX2 RNF10 RRAGA RRAGC RRAGD SNRNP40	6 interacting genes: ACP5 APP CEBPA DDR1 EIF4ENIF1 NOL8
Entrez ID		55035	9410
HPRD ID		11397	08481
Ensembl ID		ENSG00000198000	ENSG00000060688
Uniprot IDs		A6H8Z4 Q76FK4	A0MNP2 Q96DI7
PDB IDs			3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6ZYM 7ABG 7ABI 7DVQ 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RC0 8RM5 8RO2 8Y6O 9FMD
Enriched GO Terms of Interacting Partners?		Gtr1-Gtr2 GTPase Complex Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling FNIP-folliculin RagC/D GAP Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus Regulation Of TORC1 Signaling Negative Regulation Of Autophagy Response To Amino Acid Regulation Of TOR Signaling Cellular Response To Starvation Response To Starvation Protein-membrane Adaptor Activity Cellular Response To Nutrient Levels GTPase Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation GTPase Activity Protein Localization To Lysosome Protein Heterodimerization Activity RNA Splicing GTP Binding TORC1 Signaling Lysosomal Membrane Regulation Of Autophagy Negative Regulation Of Catabolic Process GDP Binding TOR Signaling Protein Localization To Vacuole Autophagosome Assembly Response To Nutrient Levels Lysosome Autophagosome Organization Regulation Of Translational Initiation Nucleoplasm Nucleus Cytoplasmic Translation Positive Regulation Of Translation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane GATOR1 Complex Vacuole Organization Organelle Assembly Negative Regulation Of Translation Cellular Response To Methionine Molecular Adaptor Activity Response To Methionine Sno(s)RNA-containing Ribonucleoprotein Complex Negative Regulation Of Schwann Cell Proliferation	Regulation Of Superoxide Anion Generation Regulation Of Superoxide Metabolic Process Regulation Of Interleukin-1 Production Defense Response To Gram-positive Bacterium Response To Peptide Regulation Of Nitric Oxide Metabolic Process Response To Cytokine Regulation Of Inflammatory Response Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Superoxide Anion Generation Regulation Of Interleukin-1 Beta Production Acetylcholine Receptor Activator Activity Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Catabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Lipoprotein Particle Memory Notch Signaling Pathway Positive Regulation Of Protein Import Developmental Cell Growth Smooth Muscle Cell-matrix Adhesion Protein Tyrosine Kinase Collagen Receptor Activity Kinase Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Reactive Oxygen Species Metabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization CHOP-C/EBP Complex Cell Maturation Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Cell Population Proliferation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response
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