FBXO34 and KRTAP4-5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FBXO34	KRTAP4-5
Description		F-box protein 34	keratin associated protein 4-5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Hair Cycle
Pathways			Keratinization
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Testicular germ cell tumor ( 28604728) Urate levels ( 31578528) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ALPP COL8A1 DISC1 FGF14 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP12-4 KRTAP4-11 KRTAP4-12 KRTAP4-5 KRTAP5-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI MTUS2 OIT3 SKP1 SMAD4 TGFBR1 VHL VWC2L	74 interacting genes: AXIN2 BAG4 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GATA1 GLRX3 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-2 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NUFIP2 OTX1 PEAR1 POTEB3 POU4F2 PRKAB2 RORB SH3GLB2 SHFL SLC4A7 SMCP TRIM42 TSPAN4 VASN YY1 ZNF552 ZNF774 ZNF835 ZNF837
Entrez ID		55030	85289
HPRD ID		16442	13946
Ensembl ID		ENSG00000178974	ENSG00000198271
Uniprot IDs		Q9NWN3	Q9BYR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Hair Cycle Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Cytosol I-SMAD Binding Regulation Of Extracellular Matrix Assembly	Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Identical Protein Binding Protein Binding
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