PPIL3 and WDR12

		PPIL3	WDR12
Description		peptidylprolyl isomerase like 3	WD repeat domain 12
Image
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor PeBoW Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding RNA Splicing	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Notch Signaling Pathway Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Regulation Of Cell Cycle
Pathways		mRNA Splicing - Major Pathway	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Lacunar stroke ( 33773637) Myocardial infarction (early onset) ( 19198609) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White matter hyperintensities ( 30002152 32358547) White matter integrity (fractional anisotropy) ( 32358547)
Interacting Genes		10 interacting genes: CENATAC DMRTB1 PCBP1 PHC1 RPS13 SHARPIN SLU7 TAB2 TAB3 YTHDF1	2 interacting genes: H1-2 NOTCH1
Entrez ID		53938	55759
HPRD ID		15163	18295
Ensembl ID		ENSG00000240344	ENSG00000138442
Uniprot IDs		A0A024R3V4 A0A0S2Z5A8 Q9H2H8	Q53T99 Q9GZL7
PDB IDs		1XYH 2OJU 2OK3 8C6J	6N31 6P0Q 8FKY
Enriched GO Terms of Interacting Partners?			Chromatin DNA Binding MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Vasculogenesis Involved In Coronary Vascular Morphogenesis Venous Endothelial Cell Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Distal Tubule Development Auditory Receptor Cell Fate Commitment Notch Signaling Involved In Heart Development Regulation Of Aorta Morphogenesis Growth Involved In Heart Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Epidermal Cell Fate Specification Endocardium Morphogenesis Coronary Sinus Valve Morphogenesis Retinal Cone Cell Differentiation Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Cardiac Right Ventricle Formation Glomerular Mesangial Cell Development Cell Migration Involved In Endocardial Cushion Formation Chemical Synaptic Transmission, Postsynaptic Foregut Morphogenesis Compartment Pattern Specification Mitral Valve Formation Arterial Endothelial Cell Differentiation Cellular Response To Tumor Cell Regulation Of Cell Adhesion Involved In Heart Morphogenesis Cardiac Vascular Smooth Muscle Cell Development Negative Regulation Of Extracellular Matrix Constituent Secretion Positive Regulation Of Aorta Morphogenesis Coronary Vein Morphogenesis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Cardiac Right Atrium Morphogenesis Cell Surface Receptor Signaling Pathway Involved In Heart Development Negative Regulation Of Endothelial Cell Chemotaxis Mesangial Cell Development Luteolysis Endocardium Development Cardiac Atrium Morphogenesis T-helper 17 Type Immune Response Endocardial Cell Differentiation Negative Regulation Of Photoreceptor Cell Differentiation Blood Vessel Endothelial Cell Differentiation Positive Regulation Of Artery Morphogenesis Inhibition Of Neuroepithelial Cell Differentiation Positive Regulation Of Apoptotic Process Involved In Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?