FXYD7 and ATP1B1

Number of citations of the paper that reports this interaction (PMID 12093728)
20

Data Source:
HPRD (in vitro)

		FXYD7	ATP1B1
Gene Name		FXYD domain containing ion transport regulator 7	ATPase, Na+/K+ transporting, beta 1 polypeptide
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Vesicle Sarcolemma Extracellular Vesicular Exosome
	Molecular Function	Ion Channel Activity ATPase Binding	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity Protein Binding MHC Class II Protein Complex Binding ATPase Binding
	Biological Process	Ion Transmembrane Transport Regulation Of Ion Transport Transmembrane Transport	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Blood Coagulation Potassium Ion Import Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Stabilization Leukocyte Migration Transmembrane Transport Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export From Cell Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import
Pathways		Ion transport by P-type ATPases Ion channel transport	Ion transport by P-type ATPases Ion channel transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			QT interval ( 23166209 19305409)
Protein-Protein Interactions		5 interactors: APOE APPBP2 ATP1A1 ATP1B1 SGTA	17 interactors: BACE1 BARD1 BRCA1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 KMT2B LRIF1 NDRG2 PAXIP1 PSME1 TRMT2A USP4
Entrez ID		53822	481
HPRD ID		09457	01663
Ensembl ID		ENSG00000221946	ENSG00000143153
Uniprot IDs		P58549	A3KLL5 A6NGH2 P05026
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Export From Cell Sodium Ion Export Cellular Potassium Ion Homeostasis Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Sodium Ion Homeostasis Relaxation Of Cardiac Muscle Membrane Repolarization Cell Communication By Electrical Coupling Potassium Ion Homeostasis Negative Regulation Of Steroid Biosynthetic Process Relaxation Of Muscle Potassium Ion Import Negative Regulation Of Steroid Metabolic Process Sodium Ion Homeostasis Blood Circulation Cardiac Muscle Cell Action Potential Negative Regulation Of Lipid Biosynthetic Process Cardiac Conduction Cardiac Muscle Contraction Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Regulation Of Sodium Ion Transport Heart Contraction Metal Ion Homeostasis Regulation Of Steroid Biosynthetic Process Regulation Of Cardiac Muscle Contraction Negative Regulation Of Lipid Metabolic Process Cellular Chemical Homeostasis Striated Muscle Contraction Regulation Of Striated Muscle Contraction Ion Homeostasis Action Potential Regulation Of Steroid Metabolic Process Regulation Of Ion Transport Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Cellular Homeostasis Regulation Of Lipid Biosynthetic Process Second-messenger-mediated Signaling Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Neurofibrillary Tangle Assembly	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Negative Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K4 Methylation Histone Lysine Methylation Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Nitrogen Compound Metabolic Process Nitric Oxide Biosynthetic Process Regulation Of Protein Metabolic Process Reactive Oxygen Species Metabolic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Histone Acetylation Histone Methylation Regulation Of Histone Modification Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Methylation Nitric Oxide Metabolic Process Positive Regulation Of Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Histone H3-K4 Methylation Protein Methylation Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Regulation Of Chromosome Organization Regulation Of Gene Expression, Epigenetic Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Histone Acetylation Negative Regulation Of Cell Death
Tagcloud ?			activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Difference) ?			activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Intersection) ?