PLOD2 and CLSTN2

		PLOD2	CLSTN2
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	calsyntenin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Rough Endoplasmic Reticulum Membrane Extracellular Matrix Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Cell Projection Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Metal Ion Binding Dioxygenase Activity	Calcium Ion Binding
	Biological Process	Response To Hypoxia Protein O-linked Glycosylation Peptidyl-lysine Hydroxylation Collagen Fibril Organization Protein Modification Process Hydroxylysine Biosynthetic Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Associative Learning Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Inhibitory Synapse Assembly
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid
Diseases		Bruck syndrome
GWAS		Height ( 31562340) Obesity-related traits ( 23251661) Squamous cell lung carcinoma ( 28604730) Zinc levels ( 26025379)	Asthma ( 27611488) Fasting insulin (dietary factor interaction) ( 24204828) Hodgkin's lymphoma ( 24920014) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Iris color (b* coordinate) ( 30895295) Letter-number span reordering ( 31596458) Lung cancer ( 28604730) Multiple sclerosis (OCB status) ( 23472185) Myopia (pathological) ( 23049088) Neuritic plaque ( 25188341) Phenylephrine infusion rate during anesthesia ( 31455332) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 25367360) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Sudden cardiac arrest ( 21658281) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		1 interacting genes: LINC01554	1 interacting genes: SNCA
Entrez ID		5352	64084
HPRD ID		03519	13077
Ensembl ID		ENSG00000152952	ENSG00000158258
Uniprot IDs		A0A994J6S5 O00469	Q9H4D0
PDB IDs
Enriched GO Terms of Interacting Partners?			Modified Amino Acid Metabolic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Hydroxylysine Biosynthetic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Procollagen Glucosyltransferase Activity Procollagen-lysine 5-dioxygenase Activity Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Rough Endoplasmic Reticulum Membrane Oxidoreductase Activity Peptidyl-lysine Hydroxylation Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Organic Acid Metabolic Process Protein Hydroxylation Carboxylic Acid Metabolic Process Regulation Of SNARE Complex Assembly Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Platelet Alpha Granule Membrane Synaptic Vesicle Priming Positive Regulation Of Receptor Recycling Response To Magnesium Ion
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