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PLOD2

Description procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Space
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Golgi Apparatus
  • Membrane
  • Rough Endoplasmic Reticulum Membrane
  • Extracellular Matrix
  • Extracellular Exosome
Molecular Function
  • Iron Ion Binding
  • Procollagen-lysine 5-dioxygenase Activity
  • Oxidoreductase Activity
  • Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen
  • L-ascorbic Acid Binding
  • Procollagen Glucosyltransferase Activity
  • Metal Ion Binding
  • Dioxygenase Activity
Biological Process
  • Response To Hypoxia
  • Protein O-linked Glycosylation
  • Peptidyl-lysine Hydroxylation
  • Collagen Fibril Organization
  • Protein Modification Process
  • Hydroxylysine Biosynthetic Process
Pathways
  • Collagen biosynthesis and modifying enzymes
Drugs
  • Ascorbic acid
Diseases
  • Bruck syndrome
GWAS
  • Height ( 31562340)
  • Obesity-related traits ( 23251661)
  • Squamous cell lung carcinoma ( 28604730)
  • Zinc levels ( 26025379)
Novel Interacting Genes 6 novel interacting genes: CENPF CLSTN2 LITAF LYPLA1 NUCB1 WWTR1
Interacting Genes 1 interacting genes: LINC01554
Entrez ID 5352
HPRD ID 03519
Ensembl ID ENSG00000152952
Uniprot IDs A0A994J6S5 O00469
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025