CHMP5 and DOP1B

		CHMP5	DOP1B
Description		charged multivesicular body protein 5	DOP1 leucine zipper like protein B
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane	Golgi Membrane Endosome Golgi Apparatus Trans-Golgi Network Cytosol Membrane Early Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Plasma Membrane Repair Regulation Of Receptor Recycling Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Lysosome Organization Mitotic Metaphase Chromosome Alignment Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Erythrocyte Differentiation Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly	Golgi To Endosome Transport Endoplasmic Reticulum Organization Embryonic Pattern Specification Protein Transport Cognition
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		17 interacting genes: APPBP2 CEBPA CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	2 interacting genes: ATP5F1B MTDH
Entrez ID		51510	9980
HPRD ID		15408	07271
Ensembl ID		ENSG00000086065	ENSG00000142197
Uniprot IDs		Q9NZZ3	Q9Y3R5
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?		Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Mitotic Cytokinetic Process Viral Budding Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Viral Budding From Plasma Membrane Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Protein-containing Complex Disassembly Regulation Of Mitotic Spindle Assembly Nuclear Membrane Reassembly Chromosome Localization Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell Endosome Organization Nuclear Pore Nucleus Organization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization ESCRT III Complex Disassembly ESCRT Complex Disassembly Membrane Fission Mitotic Metaphase Chromosome Alignment ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Nuclear Membrane Organization Multivesicular Body-lysosome Fusion Autophagosome Maturation Lysosomal Membrane Organization Metaphase Chromosome Alignment Membrane Assembly Viral Process Late Endosome Membrane Autophagy Kinetochore Endosome Vacuolar Transport Kinetochore Microtubule Midbody Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Membrane Membrane Coat Endosomal Transport
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