CRNKL1 and PPIL2

Number of citations of the paper that reports this interaction (PMID 15189447)
22

Data Source:
HPRD (in vivo, two hybrid)

		CRNKL1	PPIL2
Gene Name		crooked neck pre-mRNA splicing factor 1	peptidylprolyl isomerase (cyclophilin)-like 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytoplasm Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Golgi Lumen Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Ligase Activity Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome	Protein Polyubiquitination Protein Peptidyl-prolyl Isomerization Protein Folding Blood Coagulation Leukocyte Migration Protein Localization To Plasma Membrane
Pathways			Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BID HSP90AA1 PPIL2	7 interactors: APP BSG CALM1 CRNKL1 HSP90AA1 PRCC TRIM23
Entrez ID		51340	23759
HPRD ID		09898	08472
Ensembl ID		ENSG00000101343	ENSG00000100023
Uniprot IDs		Q5JY65 Q69YP1 Q9BZJ0	E7EW80 Q13356
PDB IDs			1ZKC
Enriched GO Terms of Interacting Partners?		Protein Localization To Membrane Mitochondrial Membrane Organization Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Membrane Organization Mitochondrial Transport Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Folding Protein Import Into Mitochondrial Outer Membrane Protein Localization Establishment Of Protein Localization To Organelle Mitochondrion Organization Glial Cell Apoptotic Process Protein Targeting Cellular Localization Positive Regulation Of Protein Homooligomerization Mitochondrial Outer Membrane Permeabilization Protein Localization To Organelle Chaperone-mediated Protein Complex Assembly Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Protein Oligomerization Hepatocyte Apoptotic Process Protein Refolding Cytoplasmic Transport Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Response To Stress Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitric Oxide Metabolic Process Regulation Of Protein Oligomerization Regulation Of Cellular Response To Heat Reactive Nitrogen Species Metabolic Process Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Intracellular Protein Transport Regulation Of Membrane Permeability Regulation Of Nitric-oxide Synthase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Complex Assembly Intracellular Protein Transmembrane Transport Neuron Apoptotic Process Positive Regulation Of Mitochondrion Organization Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Nitric-oxide Synthase Activity Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Oxidoreductase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Reactive Oxygen Species Metabolic Process Wound Healing Synaptic Growth At Neuromuscular Junction Response To Wounding Collateral Sprouting In Absence Of Injury Protein Import Into Mitochondrial Outer Membrane Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Innate Immune Response Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity Establishment Of Localization In Cell Membrane Organization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cell Cycle Immune System Process Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Small Molecule Metabolic Process Fc Receptor Signaling Pathway Neuron Remodeling Regulation Of Catalytic Activity Cellular Localization Response To Abiotic Stimulus Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Response To Metal Ion Positive Regulation Of Phosphoprotein Phosphatase Activity Chaperone-mediated Protein Complex Assembly Response To Light Stimulus Exocytosis Alcohol Metabolic Process Locomotion Protein Localization To Membrane Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Immune Response
Tagcloud ?		anatomical assumes bcc bccs binomial correction drivers exome genesis hot intermittent invex landscape lend melanomas mutational nebl passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	acidic assayed bace1 changing cleaving cyclophilin drive employing enolase fibrillary fruitful gfap glial isomerase limiting modulator mortem neuron nse peptidylprolyl proteolytic qbase qpcr quantified reticulon rtn3 secretase stably track
Tagcloud (Difference) ?		anatomical assumes bcc bccs binomial correction drivers exome genesis hot intermittent invex landscape lend melanomas mutational nebl passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	acidic assayed bace1 changing cleaving cyclophilin drive employing enolase fibrillary fruitful gfap glial isomerase limiting modulator mortem neuron nse peptidylprolyl proteolytic qbase qpcr quantified reticulon rtn3 secretase stably track
Tagcloud (Intersection) ?