MRPS2 and OBP2A

Data Source: HiPPIP (Novel)

		MRPS2	OBP2A
Name		mitochondrial ribosomal protein S2	odorant binding protein 2A
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Ribosome Small Ribosomal Subunit Ribonucleoprotein Complex	Extracellular Region Extracellular Space
	Molecular Function	Structural Constituent Of Ribosome	Odorant Binding Small Molecule Binding
	Biological Process	Translation Mitochondrial Translation Mitochondrial Ribosome Assembly	Sensory Perception Of Chemical Stimulus Sensory Perception Of Smell Glucose Homeostasis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial protein degradation Mitochondrial ribosome-associated quality control	None
Drugs		None	Tretinoin
GWAS		No GWAS studies recorded	Coagulation factor levels ( 23267103 ) Subcutaneous adipose tissue ( 29178545 ) Subcutaneous adipose tissue (sex interaction) ( 29178545 )
Novel Interactors		3 novel interactors: OBP2A SLC34A3 TOR1B	2 novel interactors: ADCY2 MRPS2
Interacting Genes		2 interacting genes: APP UBC	2 interacting genes: ADRB2 OR1G1
Entrez ID		51116	29991
HPRD ID		14783	01253
Ensembl ID		ENSG00000122140	ENSG00000122136
Uniprot IDs		Q9Y399	B7ZLH4 Q5T8A4 Q5T8A5 Q9NY56
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	4RUN
GO Terms Enriched among Interactors		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Chemical Homeostasis Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Vesicle Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Sodium-dependent Phosphate Transport Peptidase Activator Activity Cellular Response To Manganese Ion Intracellular Phosphate Ion Homeostasis Endoplasmic Reticulum Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Homeostatic Process	Adenylate Cyclase Binding Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential G Protein-coupled Olfactory Receptor Activity G Protein-coupled Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Response To Psychosocial Stress Norepinephrine Binding Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Mitochondrial Ribosome Assembly Positive Regulation Of Autophagosome Maturation Heat Generation Adrenergic Receptor Activity Diet Induced Thermogenesis CAMP Biosynthetic Process Adenylate Cyclase Activity G Protein-coupled Receptor Activity Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Multicellular Organism Growth Cellular Response To Forskolin Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Response To Forskolin Phosphorus-oxygen Lyase Activity Negative Regulation Of Muscle Contraction Neuronal Dense Core Vesicle Adrenergic Receptor Signaling Pathway Negative Regulation Of Systemic Arterial Blood Pressure Ribosome Assembly CAMP Metabolic Process Cyclic Nucleotide Biosynthetic Process Adaptive Thermogenesis Bone Resorption Small Ribosomal Subunit Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Brown Fat Cell Differentiation Mitochondrial Small Ribosomal Subunit Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential