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OBP2A and ADCY2
OBP2A
ADCY2
Description
odorant binding protein 2A
adenylate cyclase 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Membrane
Dendrite
Membrane Raft
Molecular Function
Odorant Binding
Small Molecule Binding
Nucleotide Binding
Magnesium Ion Binding
Adenylate Cyclase Activity
ATP Binding
Adenylate Cyclase Binding
Lyase Activity
Phosphorus-oxygen Lyase Activity
Manganese Ion Binding
Metal Ion Binding
Biological Process
Sensory Perception Of Chemical Stimulus
Sensory Perception Of Smell
Glucose Homeostasis
CAMP Biosynthetic Process
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cyclic Nucleotide Biosynthetic Process
Intracellular Signal Transduction
Cellular Response To Forskolin
Pathways
Glucagon signaling in metabolic regulation
PKA activation
PKA activation in glucagon signalling
Adenylate cyclase activating pathway
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G alpha (s) signalling events
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
G alpha (z) signalling events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog 'off' state
GPER1 signaling
GPER1 signaling
ADORA2B mediated anti-inflammatory cytokines production
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Tretinoin
Colforsin
Colforsin
2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE
Aurothioglucose
Diseases
GWAS
Coagulation factor levels (
23267103
)
Subcutaneous adipose tissue (
29178545
)
Subcutaneous adipose tissue (sex interaction) (
29178545
)
Anxiety and stress-related disorders (
31116379
)
Atorvastatin-induced myopathy (
31220337
)
Bipolar disorder (
31043756
34002096
24618891
)
Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder (
27890468
)
Bipolar disorder or attention deficit hyperactivity disorder (
27890468
)
Bipolar I disorder (
31043756
)
Caffeine consumption from coffee (
33287642
)
Caffeine consumption from coffee or tea (
33287642
)
Capecitabine sensitivity (
22864933
)
Coffee consumption (
31046077
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Food addiction (
27106561
)
LDL cholesterol levels in HIV infection (
33109212
)
Mean arterial pressure (alcohol consumption interaction) (
24376456
)
Oropharynx cancer (
27749845
)
Pars opercularis volume (
31530798
)
Plasma factor VII activating protease levels (
30070759
)
Posterior-cingulate cortex volume (
31530798
)
Smoking status (heavy vs never) (
26423011
)
Visceral fat (
22589738
)
Interacting Genes
2 interacting genes:
ADRB2
OR1G1
6 interacting genes:
ADCY1
ADCY5
DRD4
F2RL1
GNAS
GNG2
Entrez ID
29991
108
HPRD ID
01253
00052
Ensembl ID
ENSG00000122136
ENSG00000078295
Uniprot IDs
B7ZLH4
Q5T8A4
Q5T8A5
Q9NY56
Q08462
Q71UM8
PDB IDs
4RUN
Enriched GO Terms of Interacting Partners
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Adenylate Cyclase Binding
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine
Positive Regulation Of Mini Excitatory Postsynaptic Potential
G Protein-coupled Olfactory Receptor Activity
G Protein-coupled Receptor Signaling Pathway
Beta2-adrenergic Receptor Activity
Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure
Beta-adrenergic Receptor Activity
Response To Psychosocial Stress
Norepinephrine Binding
Positive Regulation Of Lipophagy
AMPA Selective Glutamate Receptor Signaling Pathway
Mitochondrial Ribosome Assembly
Positive Regulation Of Autophagosome Maturation
Heat Generation
Adrenergic Receptor Activity
Diet Induced Thermogenesis
CAMP Biosynthetic Process
Adenylate Cyclase Activity
G Protein-coupled Receptor Activity
Negative Regulation Of Smooth Muscle Contraction
Negative Regulation Of Multicellular Organism Growth
Cellular Response To Forskolin
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Regulation Of Autophagosome Maturation
Positive Regulation Of CAMP/PKA Signal Transduction
Response To Forskolin
Phosphorus-oxygen Lyase Activity
Negative Regulation Of Muscle Contraction
Neuronal Dense Core Vesicle
Adrenergic Receptor Signaling Pathway
Negative Regulation Of Systemic Arterial Blood Pressure
Ribosome Assembly
CAMP Metabolic Process
Cyclic Nucleotide Biosynthetic Process
Adaptive Thermogenesis
Bone Resorption
Small Ribosomal Subunit
Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal
Brown Fat Cell Differentiation
Mitochondrial Small Ribosomal Subunit
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Excitatory Postsynaptic Potential
G Protein-coupled Dopamine Receptor Signaling Pathway
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Regulation Of Protein Secretion
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Regulation Of Insulin Secretion
Regulation Of Peptide Hormone Secretion
Regulation Of Protein Transport
G Protein-coupled Receptor Signaling Pathway
Response To Ketone
Cellular Response To Lipid
CAMP Biosynthetic Process
Adenylate Cyclase Activity
Response To Alcohol
Regulation Of Hormone Secretion
Regulation Of Establishment Of Protein Localization
Regulation Of Hormone Levels
Cellular Response To Forskolin
Regulation Of Secretion By Cell
Response To Forskolin
Regulation Of Secretion
Cellular Response To Catecholamine Stimulus
Phosphorus-oxygen Lyase Activity
Cellular Response To Prostaglandin E Stimulus
Response To Catecholamine
G-protein Beta-subunit Binding
CAMP Metabolic Process
Cyclic Nucleotide Biosynthetic Process
Cellular Response To Prostaglandin Stimulus
Response To Prostaglandin E
Response To Lipid
Heterotrimeric G-protein Complex
Regulation Of Biological Quality
Nervous System Process
Cyclic Purine Nucleotide Metabolic Process
Regulation Of Protein Localization
System Process
Purine-containing Compound Biosynthetic Process
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Positive Regulation Of Renin Secretion Into Blood Stream
Glutaryl-CoA Dehydrogenase Activity
Positive Regulation Of Interleukin-1 Beta Production
Nucleoside Phosphate Biosynthetic Process
Calcium- And Calmodulin-responsive Adenylate Cyclase Activity
Negative Regulation Of Protein Secretion
Proteinase-activated Receptor Activity
Positive Regulation Of Interleukin-1 Production
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Eosinophil Degranulation
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