TVP23B and ABHD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TVP23B	ABHD6
Description		trans-golgi network vesicle protein 23 homolog B	abhydrolase domain containing 6, acylglycerol lipase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane	Mitochondrion Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Late Endosome Membrane Mitochondrial Membrane AMPA Glutamate Receptor Complex Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding	Catalytic Activity Phospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity
	Biological Process	Protein Secretion Vesicle-mediated Transport	Lipid Metabolic Process Phospholipid Catabolic Process Arachidonate Metabolic Process Negative Regulation Of Cell Migration Acylglycerol Catabolic Process Positive Regulation Of Lipid Biosynthetic Process Monoacylglycerol Catabolic Process Long-term Synaptic Depression Regulation Of Retrograde Trans-synaptic Signaling By Endocanabinoid Negative Regulation Of Cold-induced Thermogenesis Regulation Of Endocannabinoid Signaling Pathway Lysobisphosphatidic Acid Metabolic Process
Pathways			Arachidonate production from DAG
Drugs
Diseases
GWAS			Hemoglobin levels ( 32327693) Platelet count ( 27863252) Refractive error ( 32231278) Rheumatoid arthritis ( 24390342 30423114) Systemic lupus erythematosus ( 26502338 27399966)
Interacting Genes		25 interacting genes: ABHD6 CEP19 ERBB2 ERBB3 ERBB4 HSD17B11 MTNR1A PBX3 REEP4 SCN3B SHISA5 SLC10A1 SLC10A6 SLC35H1 SYT16 TIMMDC1 TLCD4 TMEM14B TMEM31 TMEM80 TMX2 YIPF1 YIPF2 YIPF4 YIPF6	6 interacting genes: CKMT2 FIS1 PCGF2 RTP2 SCAMP4 TVP23B
Entrez ID		51030	57406
HPRD ID		13293	12407
Ensembl ID		ENSG00000171928	ENSG00000163686
Uniprot IDs		J3QL63 Q9NYZ1	Q9BV23
PDB IDs			7OTS
Enriched GO Terms of Interacting Partners?		Golgi Trans Cisterna Golgi Medial Cisterna ERBB3:ERBB2 Complex ERBB2 Signaling Pathway Neuregulin Receptor Activity Membrane ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Bile Acid:sodium Symporter Activity ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Mitochondrial Membrane Trans-Golgi Network Receptor Complex ERBB Signaling Pathway Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Basolateral Plasma Membrane Bile Acid And Bile Salt Transport Endomembrane System Peripheral Nervous System Development Protein Tyrosine Kinase Activity Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Establishment Of Planar Polarity Involved In Nephron Morphogenesis Posterior Compartment Specification Anterior Compartment Pattern Formation Late Endosome Membrane Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Sodium Ion Transport Cis-Golgi Network Receptor Localization To Synapse Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Positive Regulation Of Cardiac Muscle Tissue Development Central Nervous System Morphogenesis Lysobisphosphatidic Acid Metabolic Process Positive Regulation Of Epithelial Cell Proliferation
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