TAS2R10 and RTP4

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TAS2R10	RTP4
Name		taste 2 receptor member 10	receptor transporter protein 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane Defense Response To Virus
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste	None
GWAS		No GWAS studies recorded	Impulsivity (attentional) ( 30718321 )
Interacting Genes		4 interacting genes: HERPUD2 PDCD1LG2 RTP4 SSMEM1	5 interacting genes: DERL3 OPRM1 REEP4 TAS2R10 TRARG1
Entrez ID		50839	64108
HPRD ID		11990	17136
Ensembl ID		ENSG00000121318	ENSG00000136514
Uniprot IDs		Q9NYW0	Q96DX8
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Transport Cellular Response To Morphine Regulation Of NMDA Receptor Activity Behavioral Response To Ethanol Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Opioid Receptor Signaling Pathway Negative Regulation Of Protein Localization Taste Receptor Activity Bitter Taste Receptor Activity Mitotic Nuclear Membrane Reassembly Signal Recognition Particle Binding Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Glucose Import In Response To Insulin Stimulus Vesicle Fusion To Plasma Membrane Endoplasmic Reticulum Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Transport G Protein-coupled Receptor Activity G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Cytosolic Calcium Ion Concentration Response To Morphine Regulation Of Protein Transport Regulation Of Neurotransmitter Receptor Activity G-protein Beta-subunit Binding Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Retrograde Protein Transport, ER To Cytosol Endosome To Plasma Membrane Protein Transport D-glucose Import Nuclear Envelope Organization Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Sensory Perception Nuclear Membrane Reassembly Neuropeptide Binding D-glucose Transmembrane Transport G-protein Alpha-subunit Binding Regulation Of Establishment Of Protein Localization Voltage-gated Calcium Channel Activity Sensory Perception Of Taste Hexose Transmembrane Transport Regulation Of Signaling Receptor Activity