IL20 and IL20RA

Number of citations of the paper that reports this interaction (PMID 11163236)
53

Data Source:
HPRD (in vivo)

		IL20	IL20RA
Gene Name		interleukin 20	interleukin 20 receptor, alpha
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Interleukin-20 Receptor Binding Interleukin-22 Receptor Binding	Cytokine Receptor Activity Interleukin-20 Binding
	Biological Process	Inflammatory Response Immune Response Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of JAK-STAT Cascade Regulation Of Inflammatory Response	Cytokine-mediated Signaling Pathway Regulation Of Bone Resorption Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		1 interactors: IL20RA	3 interactors: IL19 IL20 IL24
Entrez ID		50604	53832
HPRD ID		05728	05729
Ensembl ID			ENSG00000016402
Uniprot IDs		Q2THG6 Q9NYY1	B4DLR5 Q9UHF4
PDB IDs		4DOH	4DOH
Enriched GO Terms of Interacting Partners?		Regulation Of Bone Resorption Regulation Of Bone Remodeling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Tissue Remodeling	Positive Regulation Of JAK-STAT Cascade Regulation Of JAK-STAT Cascade Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inflammatory Response Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Signal Transduction Immune Response Defense Response Regulation Of Peptidyl-tyrosine Phosphorylation Interleukin-6 Biosynthetic Process Regulation Of Intracellular Signal Transduction Serine Phosphorylation Of STAT3 Protein Interleukin-6 Production Serine Phosphorylation Of STAT Protein Immune System Process Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Cellular Ketone Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Keratinocyte Differentiation Regulation Of Signaling Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Protein Phosphorylation Cytokine Biosynthetic Process Response To Stress Positive Regulation Of Osteoclast Differentiation Regulation Of Keratinocyte Differentiation Cytokine Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Epidermis Development Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cellular Response To Interleukin-4 Regulation Of Epidermal Cell Differentiation Cell Death Death Regulation Of Protein Phosphorylation Response To Interleukin-4 Positive Regulation Of Myeloid Leukocyte Differentiation
Tagcloud ?		20r1 20r2 22r1 ameliorated atherosclerosis chondrocytes cocl contralateral gbm8901 glia glioblastoma hacat hek293 hypoxia hypoxic infarcted infarction ischemic luciferase mab mcp mimicked monocytes peri psoriasis rheumatoid stained stroke
Tagcloud (Difference) ?		20r1 20r2 22r1 ameliorated atherosclerosis chondrocytes cocl contralateral gbm8901 glia glioblastoma hacat hek293 hypoxia hypoxic infarcted infarction ischemic luciferase mab mcp mimicked monocytes peri psoriasis rheumatoid stained stroke
Tagcloud (Intersection) ?