IL20RA and IL19

Number of citations of the paper that reports this interaction (PMID 11564763)
47

Data Source:
HPRD (in vivo)

		IL20RA	IL19
Gene Name		interleukin 20 receptor, alpha	interleukin 19
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interleukin-20 Binding	Cytokine Activity
	Biological Process	Cytokine-mediated Signaling Pathway Regulation Of Bone Resorption Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Inflammatory Response Immune Response Signal Transduction Interleukin-6 Biosynthetic Process Positive Regulation Of JAK-STAT Cascade Reactive Oxygen Species Metabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 20228799 21297633)
Protein-Protein Interactions		3 interactors: IL19 IL20 IL24	1 interactors: IL20RA
Entrez ID		53832	29949
HPRD ID		05729	05747
Ensembl ID		ENSG00000016402	ENSG00000142224
Uniprot IDs		B4DLR5 Q9UHF4	Q9UHD0
PDB IDs		4DOH	1N1F
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JAK-STAT Cascade Regulation Of JAK-STAT Cascade Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inflammatory Response Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Signal Transduction Immune Response Defense Response Regulation Of Peptidyl-tyrosine Phosphorylation Interleukin-6 Biosynthetic Process Regulation Of Intracellular Signal Transduction Serine Phosphorylation Of STAT3 Protein Interleukin-6 Production Serine Phosphorylation Of STAT Protein Immune System Process Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Cellular Ketone Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Keratinocyte Differentiation Regulation Of Signaling Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Protein Phosphorylation Cytokine Biosynthetic Process Response To Stress Positive Regulation Of Osteoclast Differentiation Regulation Of Keratinocyte Differentiation Cytokine Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Epidermis Development Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cellular Response To Interleukin-4 Regulation Of Epidermal Cell Differentiation Cell Death Death Regulation Of Protein Phosphorylation Response To Interleukin-4 Positive Regulation Of Myeloid Leukocyte Differentiation	Regulation Of Bone Resorption Regulation Of Bone Remodeling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Tissue Remodeling
Tagcloud ?			10b 10c 10d 11b 19l colonystimulating cxcl13 cxcl14 cxcl2 ifnalpha14 ifnalpha5 ifnalpha6 ifnalpha8 ifnepsilon1 ifnkappa ifnomega1 il13 il17beta il1alpha il22 il23alpha il24 il25 il28a il3 il31 il9 imbalanced pe
Tagcloud (Difference) ?			10b 10c 10d 11b 19l colonystimulating cxcl13 cxcl14 cxcl2 ifnalpha14 ifnalpha5 ifnalpha6 ifnalpha8 ifnepsilon1 ifnkappa ifnomega1 il13 il17beta il1alpha il22 il23alpha il24 il25 il28a il3 il31 il9 imbalanced pe
Tagcloud (Intersection) ?