DUXAP9 and SRMS

Number of citations of the paper that reports this interaction (PubMedID 30515972)
36

Data Source:
BioGRID (unspecified method)

		DUXAP9	SRMS
Description		double homeobox A pseudogene 9	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Plasma Membrane
	Molecular Function		Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Protein Binding ATP Binding Kinase Activity Transferase Activity
	Biological Process		Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Protein Deubiquitination Peptidyl-tyrosine Phosphorylation Cell Differentiation Cellular Response To Nutrient Levels Peptidyl-tyrosine Autophosphorylation TORC1 Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling
Pathways			PTK6 Down-Regulation
Drugs			Fostamatinib
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Prostate cancer ( 23535732)
Interacting Genes		10 interacting genes: CBLB CCT5 CXCR4 RPTOR SAMD9 SFN SRMS STYK1 ULK2 ULK4	5 interacting genes: DUXAP9 NCK2 NEDD4 NEDD4L SKAP2
Entrez ID		503638	6725
HPRD ID			10250
Ensembl ID			ENSG00000125508
Uniprot IDs			Q9H3Y6
PDB IDs
Enriched GO Terms of Interacting Partners?			Sodium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Neuromuscular Junction Development Receptor Metabolic Process Protein Monoubiquitination Receptor Internalization Regulation Of Dendrite Morphogenesis Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Lymphocyte Activation Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Formation Of Structure Involved In A Symbiotic Process Regulation Of Dendrite Development Leukocyte Activation Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Transmembrane Transport Cell Activation Channel Inhibitor Activity Transmembrane Transporter Binding Phosphothreonine Residue Binding Negative Regulation Of Sodium Ion Import Across Plasma Membrane Positive Regulation Of Protein Metabolic Process Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Sodium Ion Transport Receptor-mediated Endocytosis Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Caveolin-mediated Endocytosis Plasma Membrane Bounded Cell Projection Organization Nuclear Receptor-mediated Corticosteroid Signaling Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Ubiquitin-protein Transferase Activity Synapse Organization Positive Regulation Of Translation In Response To Stress Regulation Of Caveolin-mediated Endocytosis Cell Projection Organization Regulation Of Monoatomic Cation Transmembrane Transport Signal Complex Assembly Protein Polyubiquitination Negative Regulation Of Sodium Ion Transmembrane Transport
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