DUXAP9 and ULK4

Number of citations of the paper that reports this interaction (PubMedID 30515972)
36

Data Source:
BioGRID (unspecified method)

		DUXAP9	ULK4
Description		double homeobox A pseudogene 9	unc-51 like kinase 4
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function		Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process		Microtubule Cytoskeleton Organization Regulation Of Signal Transduction Regulation Of Neuron Projection Development Protein Kinase C Deactivation Regulation Of MAPK Cascade Regulation Of JNK Cascade Regulation Of P38MAPK Cascade Regulation Of Neuron Migration
Pathways
Drugs
Diseases
GWAS			Alcohol dependence ( 28714907) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Bipolar disorder x sex interaction ( 34099189) Blood pressure ( 21909110 23972371) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 19430479 27618447 27618452 30578418 27736895 27841878 28739976 28498854) Diastolic blood pressure (long-term average) ( 33603002) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Gut microbiota (functional units) ( 27694959) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lacunar stroke ( 33773637) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple myeloma ( 22120009 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 30487518 30578418 27841878 28739976) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Red blood cell count ( 32888494) Refractive error ( 32231278) Systolic blood pressure ( 30578418) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		10 interacting genes: CBLB CCT5 CXCR4 RPTOR SAMD9 SFN SRMS STYK1 ULK2 ULK4	3 interacting genes: APP DUXAP9 YWHAQ
Entrez ID		503638	54986
HPRD ID			07928
Ensembl ID			ENSG00000168038
Uniprot IDs			Q96C45
PDB IDs			6TSZ 6U5L
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Monoatomic Ion Transport Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle
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