OLR1 and CEL

Number of citations of the paper that reports this interaction (PubMedID 12857870)
73

Data Source:
BioGRID (pull down)

		OLR1	CEL
Description		oxidized low density lipoprotein receptor 1	carboxyl ester lipase
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GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Plasma Membrane Membrane Specific Granule Membrane Receptor Complex Membrane Raft Tertiary Granule Membrane	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Exosome
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding	Catalytic Activity Sterol Ester Esterase Activity Triacylglycerol Lipase Activity Protein Binding Acetylesterase Activity Heparin Binding Hydrolase Activity Retinyl-palmitate Esterase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Immune System Process Proteolysis Inflammatory Response Cell Adhesion Leukocyte Cell-cell Adhesion Blood Circulation Vesicle-mediated Transport Lipoprotein Metabolic Process	Lipid Metabolic Process Lipid Catabolic Process Pancreatic Juice Secretion Intestinal Cholesterol Absorption Retinol Metabolic Process Ceramide Catabolic Process
Pathways		Cell surface interactions at the vascular wall Neutrophil degranulation	Digestion of dietary lipid Developmental Lineage of Pancreatic Acinar Cells
Drugs			Taurocholic acid
Diseases			Maturity onset diabetes of the young (MODY)
GWAS			Blood protein levels ( 30072576) Early-onset Parkinson's disease ( 28256260) Type 1 diabetes ( 34012112)
Interacting Genes		5 interacting genes: CEL DSCR9 FBXL17 HSPA4 HUNK	3 interacting genes: BPGM LTF OLR1
Entrez ID		4973	1056
HPRD ID		04003	07509
Ensembl ID		ENSG00000173391	ENSG00000170835
Uniprot IDs		P78380	B4DSX9 O75612 P19835 Q86SR3
PDB IDs		1YPO 1YPQ 1YPU 1YXJ 1YXK 3VLG 6TL7 6TL9 6TLA 7R8U 7W5D 7XMP	1F6W 1JMY 6H0T 6H0V 6H18 6H19 6H1A
Enriched GO Terms of Interacting Partners?			Phosphoglycerate Mutase Activity Defense Response Bisphosphoglycerate Mutase Activity Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Positive Regulation Of Bone Mineralization Involved In Bone Maturation Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Phagocytic Vesicle Lumen Membrane Destabilizing Activity Negative Regulation Of Osteoclast Development Intramolecular Phosphotransferase Activity Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development Establishment Of Blood-brain Barrier Negative Regulation Of ATP-dependent Activity Cytolysis By Host Of Symbiont Cells Negative Regulation Of Membrane Potential Specific Granule Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Antifungal Humoral Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Osteoblast Proliferation Neuroinflammatory Response Inflammatory Response Oxygen Transport Host-mediated Suppression Of Viral Proces Low-density Lipoprotein Particle Receptor Activity Innate Immune Response In Mucosa Respiratory Gaseous Exchange By Respiratory System Defense Response To Other Organism Response To Stress Response To Protozoan Erythrocyte Development Defense Response To Protozoan Cysteine-type Endopeptidase Inhibitor Activity Bone Morphogenesis Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Osteoblast Proliferation Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of ATP-dependent Activity Mucosal Immune Response Negative Regulation Of Osteoclast Differentiation Killing By Host Of Symbiont Cells Organ Or Tissue Specific Immune Response Lipoprotein Metabolic Process Lipopolysaccharide Binding Biological Process Involved In Interaction With Symbiont ADP Catabolic Process ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process
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