NDUFB1 and NDUFA5

Number of citations: 0 (PubMedID 16189514)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		NDUFB1	NDUFA5
Name		NADH:ubiquinone oxidoreductase subunit B1	NADH:ubiquinone oxidoreductase subunit A5
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Nuclear Speck Respiratory Chain Complex I	Mitochondrion Mitochondrial Inner Membrane Membrane Protein-containing Complex Respiratory Chain Complex I
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Respiratory Electron Transport Chain Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis	Respiratory electron transport Complex I biogenesis RHOG GTPase cycle
Drugs		NADH	NADH
GWAS		LDL cholesterol levels x loop diuretics use interaction ( 31806883 ) Refractive error ( 32231278 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 )	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: IRF5
Interacting Genes		3 interacting genes: APP EWSR1 NDUFA5	9 interacting genes: APP CBY2 CCDC85B COG6 DAZAP2 GOLGA2 NDUFB1 PLEKHF2 TTR
Entrez ID		4707	4698
HPRD ID		11952	03398
Ensembl ID		ENSG00000183648	ENSG00000128609
Uniprot IDs		O75438	A0A024R772 A0A087WXR5 A0A087X1G1 Q16718
PDB IDs		5XTC 5XTD 5XTH 5XTI	5XTB 5XTD 5XTH 5XTI
GO Terms Enriched among Interactors		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding	Protein Serine/threonine Kinase Binding