SERPINC1 and MRPS14

		SERPINC1	MRPS14
Description		serpin family C member 1	mitochondrial ribosomal protein S14
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Extracellular Matrix Extracellular Exosome Blood Microparticle	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Small Ribosomal Subunit Ribosome Nuclear Membrane Ribonucleoprotein Complex
	Molecular Function	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Peptidase Inhibitor Activity Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Blood Coagulation Hemostasis Regulation Of Blood Coagulation	Translation Mitochondrial Translation
Pathways		Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs		Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases		Inherited thrombophilia
GWAS		Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)	Adult body size ( 32376654) Keratoconus ( 33649486) Plateletcrit ( 32888494)
Interacting Genes		7 interacting genes: F2 HSP90AA1 KLK1 KLK2 KLK6 PLG SDC2	1 interacting genes: FBXO7
Entrez ID		462	63931
HPRD ID		00122	14777
Ensembl ID		ENSG00000117601	ENSG00000120333
Uniprot IDs		P01008	O60783
PDB IDs		1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Serine-type Peptidase Activity Serine-type Endopeptidase Activity Protein Processing Peptidase Activity Negative Regulation Of Fibrinolysis Extracellular Exosome Extracellular Space Secretory Granule Regulation Of Fibrinolysis Fibrinolysis Protein Maturation MHC Class II Protein Complex Binding Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation Regulation Of Biological Quality Biological Process Involved In Interaction With Symbiont Zymogen Activation Protein Metabolic Process Negative Regulation Of Coagulation Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Extracellular Region Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Albendazole Monooxygenase Activity CTP Binding DATP Binding Regulation Of Systemic Arterial Blood Pressure Tissue Regeneration Hydrolase Activity Cellular Homeostasis Protein Transport Into Plasma Membrane Raft Positive Regulation Of Wound Healing Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Endoplasmic Reticulum Lumen Trimethylamine Monooxygenase Activity Hypotaurine Monooxygenase Activity Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Platelet Alpha Granule Lumen Proteolysis Regulation Of Cardiac Muscle Contraction Striated Muscle Contraction Endopeptidase Activity Rho GDP-dissociation Inhibitor Binding Lysosomal Lumen Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Flavin-dependent Sulfhydryl Oxidase Activity	Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Lewy Body Core Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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