MOBP and KRTAP10-11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MOBP	KRTAP10-11
Description		myelin associated oligodendrocyte basic protein	keratin associated protein 10-11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Perinuclear Region Of Cytoplasm	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding
	Biological Process	Nervous System Development
Pathways		Transcriptional Regulation by MECP2	Keratinization Keratinization
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder ( 18839057) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance ( 19734545) Cortical surface area (MOSTest) ( 32665545) Corticobasal degeneration ( 26077951) Dentate gyrus volume x schizophrenia interaction ( 31155012) Progressive supranuclear palsy ( 21685912 30089514) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		21 interacting genes: APP BOLA2 BOLA2B KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 MEOX2 SDCBP TRIM41 WAC ZNF23	63 interacting genes: ADAMTSL4 ANKS1A C22orf39 CAMK2B CATSPER1 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GLRX3 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MEOX2 MOBP NBPF19 NOTCH2NLA NUFIP2 OTX1 PLSCR1 POU4F2 PRKAB2 PRKAG1 SMCP SPATA3 SPRY1 SPRY2 TLE5 ZNF587
Entrez ID		4336	386678
HPRD ID		02973	11186
Ensembl ID		ENSG00000168314	ENSG00000243489
Uniprot IDs		A0A0S2Z3W1 Q13875	P60411 P60412
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Cytosol Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding	Keratinization Intermediate Filament Epidermis Development Keratin Filament Tissue Development Hair Cycle Identical Protein Binding Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation AMP-activated Protein Kinase Activity Protein Binding Bud Elongation Involved In Lung Branching Developmental Process Regulation Of Lens Fiber Cell Differentiation Nucleotide-activated Protein Kinase Complex Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium
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