MIR34A and RBM12B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR34A	RBM12B
Description		microRNA 34a	RNA binding motif protein 12B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome Extracellular Vesicle	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	DNA Damage Response Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Lipid Storage Negative Regulation Of Angiogenesis Negative Regulation Of Chemokine Production Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Transmembrane Transport MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Cholesterol Homeostasis Response To Axon Injury Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Differentiation Regulation Of Cell Cycle Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Vascular Wound Healing Triglyceride Homeostasis Cellular Response To Hypoxia Negative Regulation Of IP-10 Production Negative Regulation Of Smooth Muscle Cell Chemotaxis Negative Regulation Of Calcium Ion Import Programmed Cell Death In Response To Reactive Oxygen Species Positive Regulation Of Blood Vessel Endothelial Cell Differentiation Negative Regulation Of Amyloid-beta Clearance Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Cellular Senescence	Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Lean body mass ( 28552196)
Interacting Genes		102 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCB SART3 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B TRIM25 TRMT1L U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	19 interacting genes: CACNA1A MIR128-1 MIR128-2 MIR15B MIR19A MIR19B1 MIR31 MIR34A MIR363 MIR98 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7G PNN RBM10 RNF10 SASH1
Entrez ID		407040	389677
HPRD ID			14213
Ensembl ID		ENSG00000284357	ENSG00000183808
Uniprot IDs			Q8IXT5
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Metabolic Process RNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleus Regulation Of RNA Splicing Nucleoplasm Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Spliceosomal Complex Cytoplasmic Stress Granule Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome MiRNA Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Negative Regulation Of Translation TRNA Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of RNA Stability Negative Regulation Of MRNA Catabolic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process RNA Stabilization Regulation Of MRNA Stability Ligase Activity U2 SnRNP MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly Positive Regulation Of Cytoplasmic Translation	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle MRNA Destabilization Regulation Of MRNA Stability RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of RNA Stability Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Positive Regulation Of MRNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Metabolic Process Extracellular Space Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Locomotion Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Inflammatory Response Negative Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Extracellular Matrix Assembly Regulation Of Endothelial Cell Migration Negative Regulation Of Extracellular Matrix Organization Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression
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