MIR200C and STRBP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR200C	STRBP
Description		microRNA 200c	spermatid perinuclear RNA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Manchette Nucleus Cytoplasm Microtubule Cytoskeleton
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Microtubule Binding Tubulin Binding
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Neuron Projection Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Response To Endoplasmic Reticulum Stress MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Notch Signaling Pathway Regulation Of Cardiac Muscle Contraction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Interleukin-33 Production Response To Amyloid-beta Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Mesodermal Cell Differentiation Negative Regulation Of Calcium Ion Import Across Plasma Membrane	Spermatogenesis Spermatid Development Mechanosensory Behavior Cell Differentiation Cell Motility
Pathways
Drugs
Diseases
GWAS			Birth weight ( 27680694) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 31217584 31562340) Lymphocyte count ( 32888494)
Interacting Genes		89 interacting genes: AIMP2 AQR ATXN2L C1QBP CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM56 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	59 interacting genes: ADARB1 ARNT CAMK2G DAB1 EIF2AK2 HMGXB4 LRRK2 MAP4 MIR1-1 MIR1-2 MIR106A MIR122 MIR128-2 MIR138-1 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A1 MIR199A2 MIR19A MIR200A MIR200B MIR200C MIR214 MIR221 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR429 MIR7-1 MIR7-3 MIR9-1 MIR9-3 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NEIL3 RBFOX1 RBPMS RBPMS2 STAU1 THAP1 ZMAT4 ZNF346
Entrez ID		406985	55342
HPRD ID			10257
Ensembl ID		ENSG00000207713	ENSG00000165209
Uniprot IDs			A0A0S2Z5K8 Q96SI9 V9HWK4
PDB IDs			2DMY
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm Nucleus Spliceosomal Complex Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation MiRNA Binding Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Gene Expression RNA Stabilization TRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process MRNA Stabilization U2 SnRNP Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Positive Regulation Of Gene Expression CRD-mediated MRNA Stabilization Nucleolus TRNA Aminoacylation MRNA 5'-UTR Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome U2-type Prespliceosome Assembly	Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of Gene Expression Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Negative Regulation Of Locomotion RNA Destabilization Positive Regulation Of MRNA Catabolic Process Extracellular Vesicle Regulation Of Macromolecule Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Protein Metabolic Process Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Translation Regulation Of Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Locomotion Regulation Of Anatomical Structure Morphogenesis Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration
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