LSP1 and SCGB2A2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		LSP1	SCGB2A2
Description		lymphocyte specific protein 1	secretoglobin family 2A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Actin Binding Protein Binding	Protein Binding
	Biological Process	Chemotaxis Defense Response Cellular Defense Response Signal Transduction Cellular Response To Interleukin-7	Androgen Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bladder cancer ( 24163127) Breast cancer ( 20453838 17529967 23535729 29059683 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Celiac disease ( 23936387) Central corneal thickness ( 32528159) Diastolic blood pressure ( 30487518 27618452 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Granulocyte percentage of myeloid white cells ( 27863252) Hypertension ( 30487518) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte count ( 32888494) Mammographic density (dense area) ( 25342443) Mean arterial pressure ( 29403010 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (antihypertensives) ( 31015401) Medication use (beta blocking agents) ( 31015401) Methadone dose in opioid dependence ( 28115739) Milk allergy ( 25710614) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Potassium levels ( 29403010) Pulse pressure ( 30578418 27841878) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 27618452 29403010 30487518 30578418 27841878) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908 21297633)	HIV-1 viral setpoint ( 26039976) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: ACTG1 BMPR2 CFTR GREB1 IL24 KLK6 LYPD3 MAPKAPK2 SCGB2A2 SNAI1 THRSP	6 interacting genes: CASP8 CDKN2C LSP1 SCGB1D2 TREM2 VASP
Entrez ID		4046	4250
HPRD ID		01083	05712
Ensembl ID		ENSG00000130592	ENSG00000110484
Uniprot IDs		A8K7L8 P33241	Q13296 Q6NX70
PDB IDs		3BH8 4NO0 4NO2
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Proteolysis Response To Anesthetic Negative Regulation Of Canonical NF-kappaB Signal Transduction Ripoptosome Regulation Of Interleukin-1 Production Death Effector Domain Binding Regulation Of Myeloid Leukocyte Differentiation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Pyroptotic Inflammatory Response Positive Regulation Of Leukocyte Differentiation CD95 Death-inducing Signaling Complex Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Myeloid Cell Differentiation Scaffold Protein Binding Lamellipodium Regulation Of Cytokine-mediated Signaling Pathway Myeloid Leukocyte Differentiation Positive Regulation Of Inflammatory Response Regulation Of Interleukin-1 Beta Production Positive Regulation Of CD40 Signaling Pathway Positive Regulation Of Engulfment Of Apoptotic Cell Positive Regulation Of Macrophage Fusion Positive Regulation Of C-C Chemokine Receptor CCR7 Signaling Pathway Sulfatide Binding Negative Regulation Of Astrocyte Activation CXCL12-activated CXCR4 Signaling Pathway Positive Regulation Of Complement Activation, Classical Pathway Negative Regulation Of Fat Cell Proliferation Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of CD40 Signaling Pathway Positive Regulation Of CAMKK-AMPK Signaling Cascade Respiratory Burst After Phagocytosis Negative Regulation Of Autophagic Cell Death Positive Regulation Of Complement Activation Detection Of Lipoteichoic Acid Detection Of Lipopolysaccharide Excitatory Synapse Pruning Complement-mediated Synapse Pruning Positive Regulation Of Microglial Cell Migration Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Apolipoprotein A-I Binding Positive Regulation Of High-density Lipoprotein Particle Clearance Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Regulation Of CAMKK-AMPK Signaling Cascade Microglial Cell Activation Involved In Immune Response Regulation Of Astrocyte Activation Very-low-density Lipoprotein Particle Binding Positive Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of Hippocampal Neuron Apoptotic Process Positive Regulation Of Synapse Pruning
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