LSP1

Gene Name		lymphocyte-specific protein 1
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Signal Transducer Activity
	Biological Process	Movement Of Cell Or Subcellular Component Chemotaxis Cellular Defense Response Signal Transduction
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 17529967 23535729 20453838) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-protein Interactions		3 interactors: ACTG1 BMPR2 MAPKAPK2
Entrez ID		4046
HPRD ID		01083
Ensembl ID		ENSG00000130592
Uniprot IDs		P33241
PDB IDs		3BH8
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Vasoconstriction Signal Transduction By Phosphorylation Response To External Stimulus Macropinocytosis Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation Immune Response-regulating Signaling Pathway 3'-UTR-mediated MRNA Stabilization Lymphangiogenesis Lymph Vessel Morphogenesis Sensory Organ Development Pinocytosis Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Immune Response Venous Blood Vessel Development Endocytosis Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Retina Vasculature Development In Camera-type Eye Lymph Vessel Development Negative Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of DNA Biosynthetic Process Response To Stress MRNA Stabilization Innate Immune Response Regulation Of Cellular Response To Heat Activin Receptor Signaling Pathway Positive Regulation Of Phosphorylation Regulation Of Immune Response Leukotriene Metabolic Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process G2 DNA Damage Checkpoint Chondrocyte Development Positive Regulation Of BMP Signaling Pathway Platelet Aggregation Positive Regulation Of Axon Extension Positive Regulation Of Bone Mineralization Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Cartilage Development System Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Blood Vessel Remodeling Anatomical Structure Formation Involved In Morphogenesis
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