ZBTB34 and TDRKH

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZBTB34	TDRKH
Description		zinc finger and BTB domain containing 34	tudor and KH domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Cytoplasm Mitochondrion P Granule Pi-body PiP-body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Male Meiotic Nuclear Division Spermatogenesis Fertilization Cell Differentiation P Granule Organization Regulatory NcRNA-mediated Gene Silencing PiRNA Processing
Pathways			PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Eyebrow thickness ( 26926045)	Asthma ( 30929738 31619474) Coronary artery disease ( 29212778 32469254) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Hemoglobin ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		4 interacting genes: PIAS4 RNF4 TDRKH ZBTB26	7 interacting genes: FAM25A FAM25C FAM25G LANCL2 SNRNP25 ZBTB34 ZFP90
Entrez ID		403341	11022
HPRD ID		19419	15485
Ensembl ID		ENSG00000177125	ENSG00000182134
Uniprot IDs		A0A0C4DFQ2 A0A8Q3WKM1 Q8NCN2	B4DJ68 Q9Y2W6
PDB IDs			2DIQ 3FDR 5J39 6B57 6PI7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Localization To Chromatin Regulation Of Protein Localization To Chromatin PML Body Regulation Of Kinetochore Assembly Regulation Of Centromere Complex Assembly SUMO Polymer Binding Microtubule End Negative Regulation Of Protein Localization PiP-body P Granule Organization Limb Epidermis Development Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Keratinocyte Apoptotic Process Pi-body Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ubiquitin Protein Ligase Activity Vitamin D Metabolic Process SUMO Ligase Activity Transferase Complex Positive Regulation Of Protein Sumoylation	Positive Regulation Of Abscisic Acid-activated Signaling Pathway Peptide Modification
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