LCP1 and CNN3

Number of citations of the paper that reports this interaction (PMID 11591653)
37

Data Source:
HPRD (in vivo)

		LCP1	CNN3
Gene Name		lymphocyte cytosolic protein 1 (L-plastin)	calponin 3, acidic
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Phagocytic Cup Extracellular Space Cytoplasm Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Filopodium Actin Filament Bundle Ruffle Membrane Extracellular Vesicular Exosome	Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function	Actin Binding Calcium Ion Binding Identical Protein Binding Actin Filament Binding	Actin Binding Calmodulin Binding
	Biological Process	T Cell Activation Involved In Immune Response Protein Kinase A Signaling Cell Migration Organ Regeneration Regulation Of Intracellular Protein Transport Wound Healing, Spreading Of Cells Actin Filament Bundle Assembly	Epithelial Cell Differentiation Actomyosin Structure Organization
Pathways
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (other) ( 23213074)	Palmitic acid (16:0) plasma levels ( 23362303) Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions		5 interactors: AIF1 ATXN2 CNN3 GCA PRKACA	3 interactors: FYN LCP1 VKORC1
Entrez ID		3936	1266
HPRD ID		01082	03848
Ensembl ID		ENSG00000136167	ENSG00000117519
Uniprot IDs		P13796	B4DFK6 F8WA86 Q15417
PDB IDs		2D85
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Muscle Hyperplasia Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Chemotaxis Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Behavior Regulation Of Chemotaxis Histone H3-T6 Phosphorylation Negative Regulation Of Smooth Muscle Cell Chemotaxis Membrane Organization Regulation Of Behavior Positive Regulation Of Smooth Muscle Cell Chemotaxis Cellular Response To Morphine Positive Regulation Of Cell Cycle Process Cellular Response To Isoquinoline Alkaloid Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Cell Cycle Organelle Organization Positive Regulation Of Cell Migration Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Negative Regulation Of Receptor Internalization Regulation Of Tight Junction Assembly Cytoplasmic MRNA Processing Body Assembly Positive Regulation Of Locomotion Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Glucose Import Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Macrophage Differentiation Cell Communication By Electrical Coupling Involved In Cardiac Conduction Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Negative Regulation Of Transport Cellular Response To Organic Cyclic Compound Phagocytosis, Engulfment Positive Regulation Of Protein Export From Nucleus Microglial Cell Activation Regulation Of Mitotic Cell Cycle Regulation Of Monocyte Chemotaxis Cerebellar Purkinje Cell Differentiation Cell Communication By Electrical Coupling Cellular Response To Hydroperoxide Activation Of Protein Kinase A Activity Stress Granule Assembly	T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Protein Kinase A Signaling Vitamin K Metabolic Process Lymphocyte Activation Blood Coagulation Hemostasis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Leukocyte Activation Cellular Response To Platelet-derived Growth Factor Stimulus Single Organismal Cell-cell Adhesion Response To Platelet-derived Growth Factor Peptidyl-glutamic Acid Carboxylation Regulation Of Body Fluid Levels Wound Healing Organ Development Cell Activation Activated T Cell Proliferation Response To Wounding Regulation Of Defense Response To Virus By Virus Regulation Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Cell Migration Cell Motility Peptidyl-amino Acid Modification Detection Of Mechanical Stimulus Quinone Metabolic Process Drug Metabolic Process Peptidyl-tyrosine Autophosphorylation Regulation Of Cellular Localization System Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Adhesion T Cell Proliferation Locomotion Multicellular Organismal Development Actin Filament Bundle Assembly Immune Response T Cell Activation Involved In Immune Response Anatomical Structure Development Organ Regeneration Dendrite Morphogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand T Cell Costimulation Cellular Ketone Metabolic Process
Tagcloud ?		cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	acap acidic actin actomyosin associate associates caldesmon calponin coimmunoprecipitation colocalization cotargeted dibutyrate erk1 ester fibers fibroblast filaments healing nonmuscle pdbu phorbol pkc pkcalpha podosome ref52 s175 t184 whereby wound
Tagcloud (Difference) ?		cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	acap acidic actin actomyosin associate associates caldesmon calponin coimmunoprecipitation colocalization cotargeted dibutyrate erk1 ester fibers fibroblast filaments healing nonmuscle pdbu phorbol pkc pkcalpha podosome ref52 s175 t184 whereby wound
Tagcloud (Intersection) ?