FAM221B and PLSCR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM221B	PLSCR2
Description		family with sequence similarity 221 member B	phospholipid scramblase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity Metal Ion Binding
	Biological Process		Plasma Membrane Phospholipid Scrambling
Pathways
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Hip circumference ( 28552196)
Interacting Genes		14 interacting genes: ANKRD11 CCDC13 CYSRT1 EFHC2 GSC2 KPRP KRT35 KRTAP10-8 KRTAP13-1 LBX1 LCE2C LZTS2 PLSCR2 TRIM50	15 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2 TMEM132D
Entrez ID		392307	57047
HPRD ID		16675	09621
Ensembl ID		ENSG00000204930	ENSG00000163746
Uniprot IDs		A6H8Z2	Q9NRY7
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Epidermis Development Establishment Of Skin Barrier Skin Epidermis Development Negative Regulation Of Glutamatergic Neuron Differentiation Primary Ureteric Bud Growth	Keratinization Tissue Development Epidermis Development Sensory Perception Nervous System Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Behavioral Defense Response Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Semicircular Canal Formation Diencephalon Morphogenesis Isoprenoid Binding Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion System Process Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Abducens Nerve Formation Optokinetic Behavior P53 Binding
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