CLEC17A and CLDN8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLEC17A	CLDN8
Description		C-type lectin domain containing 17A	claudin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	External Side Of Plasma Membrane Cell Surface Membrane	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Anchoring Junction
	Molecular Function	Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Identical Protein Binding Fucose Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Immune Response	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Iris color (L* coordinate) ( 30895295) Low density lipoprotein cholesterol levels ( 33339817) Response to antidepressants (symptom improvement) ( 29160301) Total cholesterol levels ( 33339817)	Response to statin therapy ( 20339536)
Interacting Genes		21 interacting genes: ASGR2 ATP6V0C CLDN8 CTXN3 CXCL9 FAM3C GPR152 IGFBP5 NCK2 NINJ2 OLFM4 PELI1 PELI2 RPRM SEC23A SMIM3 TM4SF4 TMEM140 TMEM201 TMEM218 UPK2	12 interacting genes: ADAM32 ARL13B CLEC17A ERGIC3 KASH5 OPRM1 PKMYT1 SMIM3 SYNE4 TJP1 TMEM80 TRARG1
Entrez ID		388512	9073
HPRD ID		16993	10835
Ensembl ID		ENSG00000187912	ENSG00000156284
Uniprot IDs		Q6ZS10	A0A0K0K1I9 P56748
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Toll Signaling Pathway	Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Nuclear Outer Membrane
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