RFPL4A and KCNRG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RFPL4A	KCNRG
Description		ret finger protein like 4A	potassium channel regulator
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Endoplasmic Reticulum
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Gene Expression Innate Immune Response	Protein Homooligomerization Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640)	Aortic root size ( 28394258) Height ( 25282103) Type 2 diabetes ( 30718926)
Interacting Genes		1 interacting genes: KCNRG	5 interacting genes: AP5B1 CCNK DGCR6L FXR2 RFPL4A
Entrez ID		342931	283518
HPRD ID		19557	06404
Ensembl ID		ENSG00000223638	ENSG00000198553
Uniprot IDs		A6NLU0	Q8N5I3
PDB IDs		2FBE
Enriched GO Terms of Interacting Partners?		Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Negative Regulation Of Potassium Ion Transport Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Transmembrane Transport Protein Homooligomerization Regulation Of Monoatomic Cation Transmembrane Transport Protein Complex Oligomerization Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Negative Regulation Of Transport Regulation Of Monoatomic Ion Transport	Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission AP-5 Adaptor Complex AP-type Membrane Coat Adaptor Complex Cyclin/CDK Positive Transcription Elongation Factor Complex
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