KCNRG and RFPL4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCNRG	RFPL4A
Description		potassium channel regulator	ret finger protein like 4A
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum	Nucleus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Homooligomerization Negative Regulation Of Delayed Rectifier Potassium Channel Activity	Regulation Of Gene Expression Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Aortic root size ( 28394258) Height ( 25282103) Type 2 diabetes ( 30718926)	Major depressive disorder ( 23377640)
Interacting Genes		5 interacting genes: AP5B1 CCNK DGCR6L FXR2 RFPL4A	1 interacting genes: KCNRG
Entrez ID		283518	342931
HPRD ID		06404	19557
Ensembl ID		ENSG00000198553	ENSG00000223638
Uniprot IDs		Q8N5I3	A6NLU0
PDB IDs			2FBE
Enriched GO Terms of Interacting Partners?		Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission AP-5 Adaptor Complex AP-type Membrane Coat Adaptor Complex Cyclin/CDK Positive Transcription Elongation Factor Complex	Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Negative Regulation Of Potassium Ion Transport Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Transmembrane Transport Protein Homooligomerization Regulation Of Monoatomic Cation Transmembrane Transport Protein Complex Oligomerization Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Negative Regulation Of Transport Regulation Of Monoatomic Ion Transport
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