KRTAP22-1 and FOXD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP22-1	FOXD2
Description		keratin associated protein 22-1	forkhead box D2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Chromatin Nucleus
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Keratinization
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Cortical volume ( 32963231) Estimated glomerular filtration rate ( 31152163) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Male-pattern baldness ( 29146897) Microalbuminuria ( 31511532) Obesity-related traits ( 23251661) Response to anti-depressant treatment in major depressive disorder ( 22041458) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532 30910378) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Vaginal microbiome composition (L. iners) ( 32723796)
Interacting Genes		14 interacting genes: ARID5A CAMK2A CHRD CREB5 FOXD2 MEIS2 MGAT5B OTX1 RNF44 SMARCC1 SNRPC VENTX ZIC1 ZNHIT2	18 interacting genes: ARID5A CADPS CYSRT1 FOXH1 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 NOTO POU2AF1 SPMIP9 TLE5
Entrez ID		337979	2306
HPRD ID		11216	03735
Ensembl ID		ENSG00000186924	ENSG00000186564
Uniprot IDs		Q3MIV0	O60548
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Transcription Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Peptidyl-threonine Autophosphorylation DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Diencephalon Morphogenesis Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Inner Ear Morphogenesis Positive Regulation Of Macromolecule Metabolic Process Forebrain Development DNA-binding Transcription Factor Activity Regulation Of Endocannabinoid Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cardiac Muscle Myoblast Proliferation Metencephalon Development	Intermediate Filament
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