HTN3 and DNAJB11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HTN3	DNAJB11
Description		histatin 3	DnaJ heat shock protein family (Hsp40) member B11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Mitochondrion	Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Chaperone Complex Protein Folding Chaperone Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity Metal Ion Binding Molecular Adaptor Activity	Signaling Receptor Binding Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Immune System Process Biomineral Tissue Development Killing Of Cells Of Another Organism Defense Response To Bacterium Innate Immune Response Positive Regulation Of Fibroblast Proliferation Defense Response To Fungus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing	Protein Folding MRNA Modification Positive Regulation Of ATP-dependent Activity Negative Regulation Of Neurogenesis Protein Maturation
Pathways		Antimicrobial peptides	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: DNAJB11 HSPA8 MUC7	24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		3347	51726
HPRD ID		00815	07485
Ensembl ID		ENSG00000205649	ENSG00000090520
Uniprot IDs		P15516	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Folding Chaperone Complex Chaperone-mediated Autophagy Translocation Complex Disassembly Unfolded Protein Binding Protein Folding Lumenal Side Of Lysosomal Membrane Regulation Of Protein Import C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Clathrin Coat Disassembly Chaperone-mediated Autophagy Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Endoplasmic Reticulum Chaperone Complex Protein Targeting To Vacuole Involved In Autophagy Prp19 Complex Regulation Of Protein Complex Stability Negative Regulation Of NLRP3 Inflammasome Complex Assembly Misfolded Protein Binding MRNA Modification Positive Regulation Of ATP-dependent Activity MRNA Metabolic Process	Cellular Response To Stress Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Positive Regulation Of Dendrite Development Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Cellular Response To Oxidative Stress Misfolded Protein Binding Biomineral Tissue Development Response To Endoplasmic Reticulum Stress ERAD Pathway
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