HADHB and TIMM8B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HADHB	TIMM8B
Gene Name		hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	translocase of inner mitochondrial membrane 8 homolog B (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Mitochondrial Nucleoid Extracellular Vesicular Exosome	Extracellular Space Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Protein Transporter Complex
	Molecular Function	Fatty-acyl-CoA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Acetyl-CoA C-acyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Protein Complex Binding Poly(A) RNA Binding NAD Binding	Zinc Ion Binding
	Biological Process	Fatty Acid Beta-oxidation Phospholipid Metabolic Process Cardiolipin Acyl-chain Remodeling Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Protein Targeting To Mitochondrion Sensory Perception Of Sound Cellular Protein Metabolic Process Chaperone-mediated Protein Transport
Pathways		Acyl chain remodeling of CL Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Mitochondrial Fatty Acid Beta-Oxidation Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Glycerophospholipid biosynthesis Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of myristoyl-CoA to lauroyl-CoA Phospholipid metabolism	Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANXA7 APP CDKN1A CHCHD4 COX17 GRB7 RCC1 SMN1 SUOX TIMM8B TK1 TNNI3K	2 interactors: EGFL8 HADHB
Entrez ID		3032	26521
HPRD ID		00887	16228
Ensembl ID		ENSG00000138029	ENSG00000150779
Uniprot IDs		B4E2W0 F5GZQ3 P55084	G3XAN8 Q9Y5J9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Intermembrane Space Fetal Process Involved In Parturition Protein Localization To Mitochondrion Regulation Of Mitotic Cell Cycle Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Hemostasis Collateral Sprouting In Absence Of Injury Cellular Component Assembly Regulation Of Cell Cycle Process Digestive Tract Development Collateral Sprouting Axon Midline Choice Point Recognition Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Intestinal Epithelial Cell Maturation Cell Maturation Digestive System Development Regulation Of Body Fluid Levels Mitochondrial Transport Response To Glucocorticoid G1/S Transition Of Mitotic Cell Cycle Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Response To Cortisol Thymidine Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Corticosteroid Ribonucleoprotein Complex Assembly Axon Choice Point Recognition Response To Toxic Substance Cellular Response To UV-B Chaperone-mediated Protein Transport Deoxyribonucleoside Monophosphate Biosynthetic Process Positive Regulation Of Ran GTPase Activity Neuron Remodeling Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Stress-induced Premature Senescence Protein Maturation By Protein Folding Regulation Of Cell Cycle Phase Transition	Cardiolipin Acyl-chain Remodeling Cardiolipin Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Glycerophospholipid Biosynthetic Process Lipid Modification Carboxylic Acid Catabolic Process Phospholipid Biosynthetic Process Lipid Catabolic Process Glycerophospholipid Metabolic Process Fatty Acid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process
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