HADHB and CHCHD4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		HADHB	CHCHD4
Description		hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta	coiled-coil-helix-coiled-coil-helix domain containing 4
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Mitochondrial Nucleoid	Mitochondrion Mitochondrial Intermembrane Space
	Molecular Function	RNA Binding (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein-containing Complex Binding Acetyl-CoA C-myristoyltransferase Activity LncRNA Binding	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Gene Expression Cellular Response To Lipopolysaccharide	Protein Transport Mitochondrial Respiratory Chain Complex Assembly Protein Import Into Mitochondrial Intermembrane Space Protein Maturation Establishment Of Protein Localization To Mitochondrion Mitochondrial Disulfide Relay System
Pathways		Acyl chain remodeling of CL Beta oxidation of myristoyl-CoA to lauroyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Mitochondrial protein import
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: ANXA7 APP CDC42 CDKN1A CEBPA CHCHD4 COX17 DDX17 GRB7 HSD17B10 HSPB2 RCC1 SMN1 SUOX TIMM8B TK1 TNNI3K UBC	2 interacting genes: CIAPIN1 HADHB
Entrez ID		3032	131474
HPRD ID		00887	13045
Ensembl ID		ENSG00000138029	ENSG00000163528
Uniprot IDs		F5GZQ3 P55084	Q8N4Q1
PDB IDs		5ZQZ 5ZRV 6DV2	2K3J 2L0Y 8VGY
Enriched GO Terms of Interacting Partners?		Mitochondrial Intermembrane Space	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-myristoyltransferase Activity Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Acetyl-CoA C-acyltransferase Activity Mitochondrial Envelope LncRNA Binding 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Mitochondrial Nucleoid 4 Iron, 4 Sulfur Cluster Binding Fatty Acid Beta-oxidation Electron Transfer Activity Mitochondrion Fatty Acid Catabolic Process Fatty Acid Oxidation Mitochondrial Intermembrane Space Iron-sulfur Cluster Binding Lipid Oxidation
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