SLC40A1 and HAMP

Number of citations of the paper that reports this interaction (PMID 15514116)
532

Data Source:
HPRD (in vivo)

		SLC40A1	HAMP
Gene Name		solute carrier family 40 (iron-regulated transporter), member 1	hepcidin antimicrobial peptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Multivesicular Body Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Basolateral Plasma Membrane	Extracellular Region Apical Cortex
	Molecular Function	Iron Ion Transmembrane Transporter Activity Protein Binding	Hormone Activity
	Biological Process	Lymphocyte Homeostasis Endothelium Development Cellular Iron Ion Homeostasis Anatomical Structure Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Iron Ion Transmembrane Transport Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Transport Spleen Trabecula Formation Multicellular Organismal Iron Ion Homeostasis	Cellular Iron Ion Homeostasis Immune Response Killing Of Cells Of Other Organism Defense Response To Bacterium Defense Response To Fungus
Pathways		Metal ion SLC transporters Iron uptake and transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GOLM1 HAMP	3 interactors: CKAP4 SLC40A1 VKORC1
Entrez ID		30061	57817
HPRD ID		05229	05925
Ensembl ID		ENSG00000138449
Uniprot IDs		Q9NP59	P81172
PDB IDs			1M4E 1M4F 2KEF 3H0T
Enriched GO Terms of Interacting Partners?		Killing Of Cells Of Other Organism Defense Response To Fungus Response To Fungus Cellular Iron Ion Homeostasis Iron Ion Homeostasis Nucleus Organization Transition Metal Ion Homeostasis	Spleen Trabecula Formation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Vitamin K Metabolic Process Cellular Response To Iron Ion Peptidyl-glutamic Acid Carboxylation Iron Ion Transmembrane Transport Multicellular Organismal Iron Ion Homeostasis Response To Iron Ion Quinone Metabolic Process Drug Metabolic Process Spleen Development Trabecula Morphogenesis Lymphocyte Homeostasis Iron Ion Transport Cellular Ketone Metabolic Process Cellular Iron Ion Homeostasis Leukocyte Homeostasis Endothelium Development Vitamin Metabolic Process Iron Ion Homeostasis Cellular Response To Metal Ion
Tagcloud ?		adrenal alternatively anaemia autosomal chelating cirrhosis cousins deferasirox deferoxamin develops export extremely ferritin ferroportin gland hemochromatosis hepcidin histologically hyperferritinaemia mother overload phlebotomies pituitary saturation spleen synonym t2 transferrin weighting	anchored bacterial balancing bound communication completely cytosolic delimited diverse domains foreign hamps input intersection language localized machinery membrane modules operate organization output predominantly sensor sensors signal summarized transducers universal
Tagcloud (Difference) ?		adrenal alternatively anaemia autosomal chelating cirrhosis cousins deferasirox deferoxamin develops export extremely ferritin ferroportin gland hemochromatosis hepcidin histologically hyperferritinaemia mother overload phlebotomies pituitary saturation spleen synonym t2 transferrin weighting	anchored bacterial balancing bound communication completely cytosolic delimited diverse domains foreign hamps input intersection language localized machinery membrane modules operate organization output predominantly sensor sensors signal summarized transducers universal
Tagcloud (Intersection) ?