GUCA1B and GUCY2F

Number of citations: 0 (PubMedID 9698373)
Data Source: HPRD (in vitro)

		GUCA1B	GUCY2F
Name		guanylate cyclase activator 1B	guanylate cyclase 2F, retinal
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleoplasm Plasma Membrane Cilium Microtubule Cytoskeleton Membrane Nuclear Membrane Ciliary Basal Body Cell Projection Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment	Nuclear Outer Membrane Plasma Membrane Membrane Cell Projection Photoreceptor Disc Membrane Rod Photoreceptor Outer Segment
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity Metal Ion Binding	Nucleotide Binding Peptide Receptor Activity Guanylate Cyclase Activity Protein Kinase Activity ATP Binding GTP Binding Lyase Activity Phosphorus-oxygen Lyase Activity Signaling Receptor Activity Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Receptor Guanylyl Cyclase Signaling Pathway Cell-cell Signaling Body Fluid Secretion Visual Perception Phototransduction Regulation Of Signal Transduction	CGMP Biosynthetic Process Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Cyclic Nucleotide Biosynthetic Process CGMP-mediated Signaling Regulation Of Opsin-mediated Signaling Pathway Intracellular Signal Transduction Detection Of Light Stimulus Involved In Visual Perception
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	Inactivation, recovery and regulation of the phototransduction cascade
Diseases		Retinitis pigmentosa (RP)	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		3 interacting genes: GUCY2D GUCY2F OTX2	1 interacting genes: GUCA1B
Entrez ID		2979	2986
HPRD ID		03783	02078
Ensembl ID		ENSG00000112599	ENSG00000101890
Uniprot IDs		Q9UMX6	P51841
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Peptide Receptor Activity Guanylate Cyclase Activity Receptor Guanylyl Cyclase Signaling Pathway Regulation Of Opsin-mediated Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Phosphorus-oxygen Lyase Activity Photoreceptor Disc Membrane Cyclic Nucleotide Biosynthetic Process CGMP-mediated Signaling Nuclear Outer Membrane Cyclic Purine Nucleotide Metabolic Process Purine Ribonucleotide Biosynthetic Process Lyase Activity Ribose Phosphate Biosynthetic Process Regulation Of G Protein-coupled Receptor Signaling Pathway Purine Nucleotide Biosynthetic Process Visual Perception Sensory Perception Of Light Stimulus Nucleotide Biosynthetic Process Purine-containing Compound Biosynthetic Process Signaling Receptor Activity Nucleoside Phosphate Biosynthetic Process Purine Ribonucleotide Metabolic Process Positive Regulation Of Gastrulation Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Eukaryotic Initiation Factor 4E Binding Rod Photoreceptor Outer Segment Protein-containing Complex Binding GTP Binding Purine Nucleotide Metabolic Process Photoreceptor Outer Segment Membrane Primitive Streak Formation Nucleotide Metabolic Process Regulation Of Gastrulation Sensory Perception Carbohydrate Derivative Biosynthetic Process Purine-containing Compound Metabolic Process Positive Regulation Of Embryonic Development Protein Kinase Activity Detection Of Light Stimulus Involved In Visual Perception Organophosphate Biosynthetic Process Nucleoside Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Protein Sequestering Activity	Negative Regulation Of Nitric-oxide Synthase Activity Alpha-galactosidase Activity Guanylate Cyclase Regulator Activity Glycosylceramide Catabolic Process Regulation Of Nitric-oxide Synthase Activity Glycoside Catabolic Process Cone Photoreceptor Outer Segment Calcium Sensitive Guanylate Cyclase Activator Activity Negative Regulation Of Oxidoreductase Activity Glycosylceramide Metabolic Process Glycosphingolipid Catabolic Process Glycolipid Catabolic Process Ceramide Catabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Oxidoreductase Activity Photoreceptor Disc Membrane Receptor Guanylyl Cyclase Signaling Pathway Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Sphingolipid Catabolic Process Phototransduction Membrane Lipid Catabolic Process Oligosaccharide Metabolic Process Glycosphingolipid Metabolic Process Photoreceptor Inner Segment Detection Of Light Stimulus Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Photoreceptor Outer Segment Hydrolase Activity, Acting On Glycosyl Bonds Body Fluid Secretion Glycolipid Metabolic Process Ceramide Metabolic Process Azurophil Granule Lumen Lysosomal Lumen Detection Of Abiotic Stimulus Sphingolipid Metabolic Process