GUCA1B

Description		guanylate cyclase activator 1B
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleoplasm Plasma Membrane Cilium Microtubule Cytoskeleton Membrane Nuclear Membrane Ciliary Basal Body Cell Projection Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity Metal Ion Binding
	Biological Process	Receptor Guanylyl Cyclase Signaling Pathway Cell-cell Signaling Body Fluid Secretion Visual Perception Phototransduction Regulation Of Signal Transduction
Pathways		Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS
Novel Interacting Genes		1 novel interacting genes: NFKBIE
Interacting Genes		3 interacting genes: GUCY2D GUCY2F OTX2
Entrez ID		2979
HPRD ID		03783
Ensembl ID		ENSG00000112599
Uniprot IDs		Q9UMX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Receptor Activity Guanylate Cyclase Activity Receptor Guanylyl Cyclase Signaling Pathway Regulation Of Opsin-mediated Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Phosphorus-oxygen Lyase Activity Photoreceptor Disc Membrane Cyclic Nucleotide Biosynthetic Process CGMP-mediated Signaling Nuclear Outer Membrane Cyclic Purine Nucleotide Metabolic Process Purine Ribonucleotide Biosynthetic Process Lyase Activity Ribose Phosphate Biosynthetic Process Regulation Of G Protein-coupled Receptor Signaling Pathway Purine Nucleotide Biosynthetic Process Visual Perception Sensory Perception Of Light Stimulus Nucleotide Biosynthetic Process Purine-containing Compound Biosynthetic Process Signaling Receptor Activity Nucleoside Phosphate Biosynthetic Process Purine Ribonucleotide Metabolic Process Positive Regulation Of Gastrulation Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Eukaryotic Initiation Factor 4E Binding Rod Photoreceptor Outer Segment Protein-containing Complex Binding GTP Binding Purine Nucleotide Metabolic Process Photoreceptor Outer Segment Membrane Primitive Streak Formation Nucleotide Metabolic Process Regulation Of Gastrulation Sensory Perception Carbohydrate Derivative Biosynthetic Process Purine-containing Compound Metabolic Process Positive Regulation Of Embryonic Development Protein Kinase Activity Detection Of Light Stimulus Involved In Visual Perception Organophosphate Biosynthetic Process Nucleoside Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Protein Sequestering Activity
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